| 光谱学与光谱分析 |
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| Measurement and Analysis of Absorption Spectrum of Human Blood |
| ZHAO Zhi-min,XIN Yu-jun, WANG Le-xin, ZHU Wei-hua,ZHENG Min,GUO Xin |
| College of Science, Nanjing University of Aeronautics & Astronautics, Nanjing 210016, China |
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Abstract The present paper puts forward a method of disease diagnosis by using the technology of spectrum analysis of human blood serum. The generation mechanism of absorption spectrum is explained and the absorption spectra of the normal blood serum and the sick blood serum are listed from the experiments of absorption spectrometry. Though the value of absorbency of the sick blood serum is almost equal to that of the normal blood serum in the most absorption spectra, there are some differences around 278 nm in the absorption spectrum. The absorbency of the blood serum with hyperglycemia is greater than that of the normal blood serum at 285 nm in the spectrum, and besides, there comes a peak shift of absorption with hyperglycemia. In the absorption spectrum of the blood serum with hypercholesterolemia，there is a clear absorption peak at 414 nm. However there is not any peak at that wavelength in the absorption spectrum of the normal blood serum. Through comparing the characters of the spectrum, we can judge if the blood sample is or not, and this blood analysis is a new method for the diagnosis of disease. Compared with other methods of blood measurements, the method of absorption spectrum analysis of blood serum presented in this paper, is more convenient for measurement, simpler for analysis, and easier to popularize.
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Received: 2006-06-26
Accepted: 2006-09-28
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Corresponding Authors:
ZHAO Zhi-min
E-mail: zhaozhimin@nuaa.edu.cn
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[1] Koji Nakanshi, Solomon P H. Infrared Absorption Spectroscopy. USA: Holden Day Inc., 1977.
[2] Vonach R, Buschmann J，Falkowski R, et al. Applied Spectroscopy，1998，52(6)：820.
[3] Budinova G, Salva J, Volka K. Applied Spectroscopy，1997，51(5)：631.
[4] SHEN Shi-jie, LIU Bing-yu, LI Qing, et al(沈世杰，刘炳玉，李 清，等). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2000，20(1)：28.
[5] YU Chang-qing，LIU Fan-guang，GU Ying，et al(于常青，刘凡光，顾 瑛，等). Chinese Journal of Laser Medicine & Surgery(中国激光医学杂志)，2004，13(1)：41.
[6] ZHAO Zhi-min，GUO Lin-feng，YU Xiao-lei，et al(赵志敏，郭林峰，俞晓磊，等). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2005，25(12)：2056.
[7] LIN Shang-zhong，CHEN Rong，XU Shao-feng(林上忠，陈 荣，许少锋). Chinese Journal of Physical Medicine(中华物理医学杂志)，1998，20(1)：26.
[8] ZHAO Zhi-min，CHEN Yu-ming，YU Xiao-lei(赵志敏，陈玉明，俞晓磊). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2003，23(5)：922.
[9] WANG Le-xin，ZHAO Zhi-min，YAO Hong-bing，et al(王乐新，赵志敏，姚红兵，等). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2002，22(6)：980.
[10] XIE Ji-yun，JIANG Zhi-liang，ZHONG Fu-xin，et al(谢济运，蒋治良，钟福新，等). Analysis and Testing Technology and Instruments(分析测试技术与仪器)，2000，6(3)：178.
[11] Lü Li-na, LIU Rong, ZHOU Ding-wen(吕丽娜，刘 蓉，周定文). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2005，25(12)：1950. |
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