| 光谱学与光谱分析 |
|
|
|
|
|
| The Fluorescence Characteristics of Micelle Inclusion of Pefloxacin and Its Application |
| DU Li-ming, WANG Jing-ping, WANG Cai-xia |
| Analytical and Testing Center, Shanxi Teacher′s University, Linfen 041004, China |
|
|
|
|
Abstract A new highly sensitive fluorescence spectrophotometic method for the determination of pefloxacin (PEFX) has been developed based on micella enhancement. The fluorescence characteristic of micelle inclusion complex formed between PEFX and sodium dodecyl sulfate (SDS) was studied. Different variables and parameters affecting the fluorescence were studied and optimized. Experiments show that sodium dodecyl sulfate can enhance greatly the fluorescence signal for pefloxacin in pH 5 Britton Robinson(BR) buffer solution. The fluorimetric method allows the determination of 0.06-1.20 μg·mL-1 of pefloxacin with SDS in aqueous solution with λex=278 nm and λem=432 nm, respectively. The detection limit for PEFX is 0.06 μg·mL-1, The recoveries are 98.5％-100.8% and the RSDs are 1.4％-2.3%. The proposed procedures could be applied successfully to the determination of the pefloxacin drugs in tablets and human plasma with good recovery. In this paper we determined pefloxacin in human plasma by synchronization-derivative fluorescence spectroscopic techniques with good analytical selectivity，high sensitivity, high capability of eliminatinｇ blank interference and improvinｇ the limit of detection.
|
|
Received: 2002-08-05
Accepted: 2002-12-20
|
|
|
|
Corresponding Authors:
DU Li-ming
|
|
| Cite this article: |
|
DU Li-ming,WANG Jing-ping,WANG Cai-xia. The Fluorescence Characteristics of Micelle Inclusion of Pefloxacin and Its Application [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2004, 24(07): 855-857.
|
|
|
|
| URL: |
|
http://www.gpxygpfx.com/EN/Y2004/V24/I07/855 |
[1] Jelikic-Stankov M, Veselinovic D, Malesev D et al. J. Pharm. Bio. Anal., 1989, 7(12): 1571.
[2] Samia M, Mohamed El-S, Esmail A A. J. Pharm. Bio. Anal., 2002, 20(1): 173.
[3] Montay G, Blain Y, Roquet F et al. J. Chromatogr B，1983, 272: 359.
[4] Raj S Ｖ, Kapadia S U, Argekar A P. Indian Drugs.，1997, 34(10): 585.
[5] Veiopoulou C J, Ioannou P C, Lianidou E S. J. Pharm. Bio. Anal., 1997, 15(12): 1839.
[6] Jelikis S M, Stankov D, Djurdjevic P. Pharmazie, 1999, 54(1): 73.
[7] DU Li-ming，JIN Ｗei-jｕn，DONG Chｕan et al(杜黎明，晋卫军, 董 川等). Spetroscopy and Spectral Analysis(光谱学与光谱分析), 2001, 21(4): 518.
|
| [1] |
CAO Yao-yao1, 2, 4, LI Xia1, BAI Jun-peng2, 4, XU Wei2, 4, NI Ying3*, DONG Chuang2, 4, ZHONG Hong-li5, LI Bin2, 4*. Study on Qualitative and Quantitative Detection of Pefloxacin and
Fleroxacin Veterinary Drugs Based on THz-TDS Technology[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(06): 1798-1803. |
| [2] |
ZHU Jun, LI Ye-ping, ZOU Jin-shan, CHEN Fang-yuan, LIU Fu-ming, YAN Xing-rong, TAN Yu-xin, ZHAI Hao-ying*. Determination of Pefloxacin by the Fluorescence Resonance Energy Transfer Effect Between Carbon Dots-Eosin B[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2019, 39(08): 2554-2560. |
| [3] |
HOU Jun-feng1, LI Xin-xia2, SHEN Xue-ru1, Miliban Huojia1, GUAN Ming1* . Determination of H2S in Rat Intestinal Perfusion Solution Based on Fluorescence Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2015, 35(08): 2217-2220. |
| [4] |
LU Kui1，2, CHENG Hong-li1, MA Li1, ZHAO Dong-xin1, YANG Liang-ru1, ZHAO Yu-fen3 . Study on the Interaction of L-Cysteine Dipeptide with DNA[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2010, 30(01): 146-149. |
| [5] |
MA Hong-yan,ZHANG She-zheng,CHEN Xiao-li,QI Guang-cai,GUO Ying,ZHANG Hu. The Fluorescence Characteristics of Troxerutin in Micellar System and Their Application[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(08): 1622-1624. |
| [6] |
SHEN Xiao-shu, GUO Lei*, GU Ming-song, FENG Jian-lin, XIE Jian-wei . Rapid Determination of Tetrodotoxin Using Microwave Assisted Alkaline Hydrolysis and Spectrofluorometric Analysis [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(12): 2264-2267. |
| [7] |
HE Hua1,WANG Ling-li1,LIU Xu-hui2,JIAO Qing-cai3,CHUONG Pham-Huy4,WANG Guang-ji1* . Fluorescence Characteristic of Terbium-Ciprofloxacin Complex and Its Application [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(08): 1516-1519. |
| [8] |
HUANG Yan-sheng1, ZHI Yan-fang1, KONG Shen-yan2, WANG Qiu-lin1, XU Bo-shi3 , WANG Shu-ren1* . Plasma Glutathione of Patients with Coronary Heart Disease Measured by Fluorospectrophotometer [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(05): 936-940. |
| [9] |
HE Hua1,YE Hai-ying1,DAI Li1,JIAO Qing-cai2,CHUONG Pham-Huy3 . Study on the Interaction of Lomefloxacin Terbium Complex and Bovine Serum Albumin by Fluorescence Spectra [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(03): 480-483. |
| [10] |
XU Li-ying, YU Wen-qing. The Fluorescence Characteristics of Norfloxacin and Its Application [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2004, 24(12): 1615-1617. |
| [11] |
LI Gui-zhi1，LIU Yong-ming1，LI Gai-zhi2 . Study on Fluorescence Characteristics of Pefloxacin-La(Ⅲ) Complex and Its Application [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2004, 24(09): 1086-1088. |
| [12] |
GUO Liang-qia, XIE Zeng-hong*, LIN Xu-cong, KE Zi-hou, CHEN Guo-nan . Direct Fluorophotometric and Flow-Injection Fluorophotometric Methods for the Determination of Trace Ammonia [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2004, 24(07): 851-854. |
| [13] |
ZHOU Jing, DU Li-ming*, CHEN Cai-ping . Fluorescence Characteristics of Tb3+-Pefeoxacin and Determination of Pefeoxacin [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2004, 24(06): 717-719. |
| [14] |
LI Gui-zhi，LIU Yong-ming . Study on Fluorescence Characteristics of Pefloxacin Based on Charge Transfer Reaction [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2004, 24(05): 600-602. |
|
|
|
|
