光谱学与光谱分析 |
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Antioxidant Activity and Spectroscopic Behavior Study with DNA of Several Salen Mn(Ⅱ),Eu(Ⅲ) Complexes |
ZHOU Hua-lei1, DONG Yi-fan2, YANG Yun-xu1*, DENG Xiao-rong1, LU Yi-qiang1 |
1. Department of Chemistry, University of Science and Technology Beijing, Beijing 100083, China 2. Department of Chemistry, Henan Experimental High School, Zhengzhou 450002, China |
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Abstract Five kinds of Salen Mn(Ⅱ) and two kinds of Eu(Ⅲ) complexes were synthesized. Under the system of NBT/L-methionine, which creats and detects O·-2, the complexes of antioxidant activity were studied, and the conclusion revealed that all Mn(Ⅱ) complexes have obvious antioxidant activity. The fluorescence study indicated that all the Salen metal complexes could bind with DNA, which shows their potential anticancer activity.
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Received: 2009-12-10
Accepted: 2010-03-20
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Corresponding Authors:
YANG Yun-xu
E-mail: yxyang@sas.ustb.edu.cn
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