光谱学与光谱分析 |
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Metallic Elemental Analysis of Tibetan Herbal Medicines and Tibetan Medicine Preparations by Synchrotron Radiation X-Ray Fluorescence |
YANG Hong-xia, LI Cen, DU Yu-zhi, WEI Li-xin* |
Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Xining 810001, China |
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Abstract To discuss the relationship between metallic element and disease through determine the elementals in Tibetan Herbal Medicines and Tibetan Medicine Preparations that have obvious effect on hepatobiliary diseases by Synchrotron Radiation X- ray Source, then to reveal the substance foundation of pharmacological action. The results show that all the Tibetan Herbal Medicines used in the experiment have the 9 kinds of metallic elements of potassium(K), calcium(Ca), titanium(Ti), vanadium(V), chromium(Cr), manganese(Mn), ferrum(Fe), zinc(Zn) and lead(Pb), the content of the elements are in the ppb or ppm level though the element constitute and the content have obvious difference. Tibetan Medicine Preparations have another 6 kinds of metallic elements of nickel(Ni), copper(Cu), rubidium(Rb), mercury(Hg), cobalt(Co), gallium(Ga) and 1 kind of nonmetallic elements of arsenic(As) when compare with Herbal Medicines, and the element constitute and the content also have obvious difference. Take advantage of SR-XRF, the test gets the basic data of elements of Tibetan Herbal Medicines and Preparations,supply the scientific support to discuss the interaction of pharmacological mechanism and the metallic elements, and find the suitability of the technique for the metallic elements detection in Tibetan Medicines.
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Received: 2014-03-13
Accepted: 2014-06-25
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Corresponding Authors:
WEI Li-xin
E-mail: lxwei@nwipb.cas.cn
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[1] Sparks C J. X-Ray Fluorescence Microprobe for Chemical Analysis. Springer-Verlag. US, New York: Plenum, 1980, 459. [2] LI Xue-jun, CHAO Zhi-yu, XIAN Ding-chang(李学军, 巢志瑜, 冼鼎昌). Physics(物理), 1993, 22: 53. [3] ZHANG Jia-hua, XU Jun-quan, ZHU Jie-qing (张家骅, 徐君权, 朱节清). X-Ray Fluorescence Analysis of Radioisotope(放射性同位素X射线荧光分析). Beijing: Atomic Energy Press(北京:原子能出版社), 1981. [4] LI Xue-jun, CHAO Zhi-yu, XIAN Ding-chang(李学军, 巢志瑜, 冼鼎昌). Physics(物理), 1992, 29(2): 553. [5] Jones K W, Gordon B M. Analytical Chemistry,1989, 61: 341A. [6] Karan M, Vasisht K, Handa S S. Phytotherapy Research, 1999, 13: 24. [7] Karan M, Vasisht K, Handa S S. Phytotherapy Research, 1999, 13: 95. [8] Hase K, Quanbo X, Basnet P, et al. Biochemical Pharmacology,1999, 57: 1431. [9] Hajimehdipoor H, Sadeghi Z, Elmi S, et al. Journal of Pharmacy and Pharmacology, 2006, 58: 277. [10] Li Jianchen, Feng Li, Sun Baohui, et al. Biological & Pharmaceutical Bulletin, 2005, 28(3): 534. [11] Kotoky J, Das P N. Fitoterapia, 2008, 79: 384. [12] Zalups R K, Koropatnick J. Cellular and Molecular Biology of Metals. New York: CRC Press, 2010. [13] Ritland S, Aaseth J. Acta Pharmacologicaet Toxicologica, 1986, 59(Supplement s7): 195. [14] Plautha M, Cabréb E, Campilloc B, et al. Clinical Nutrition, 2009, 28(4) : 436. [15] Tuerk M J, Fazel N. Curr. Opin. Gastroentero, 2009, 25(2): 136. [16] MIAO Jian(苗 健). Trace Elements and Related Diseases(微量元素与相关疾病). Zhengzhou: Henan Medical University Press(郑州: 河南医科大学出版社),1998. 123. [17] PAN Qun, XIE Zhi-chun(潘 群, 谢志春). Journal of Clinical and Experimental Medicine(临床和实验医学杂志), 2006, 10(5): 1629. [18] LIU Yun-dong, JIA Xiao-ying, WANG Xue-min(刘运东, 贾晓莹, 王学敏). Studies of Trace Elements and Health(微量元素与健康研究), 2000, 17(1): 26. [19] CHEN Xiao, ZHANG Yong-hong, CHANG De-cheng(陈 晓,张永宏, 常德成). Chinese Journal of Experimental and Clinical Virology(中华实验和临床病毒学杂志), 2002, 16(4): 344. [20] LIU De-gong, GAO Li-juan, WANG Zhong, et al(刘德恭,高丽娟, 王 忠, 等). Chinese Journal of Experimental and Clinical Virology(中华实验和临床病毒学杂志), 1997, 11(3): 246.
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