太赫兹超材料生物传感器的应用研究进展

doi:10.3964/j.issn.1000-0593(2021)06-1669-09

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Abstract Terahertz (THz) wave, refers to the frequency range of 0.1~10 THz electromagnetic wave located in the electromagnetic spectrum between infrared and microwave. The photon energy of the Terahertz wave is lower than that of visible light, and the corresponding energy of 1 THz is only about 4.14 meV, which means the damage caused by radiation to tissues and organs in living organisms would be reduced greatly and will not ionize the biological molecules. Therefore, this band has important potential application value in basic science, human security, dangerous goods detection, high-speed communication and medical imaging. In the application of medical and biological detection, it is usually necessary to detect trace amounts of analytes, which requires higher sensitivity and detection accuracy. However, the existing detection methods are affected by the low reliability of terahertz wave intensity detection. Metamaterial-based biosensing can achieve sub-wavelength resolution by enhancing local electromagnetic resonance, which greatly improves the sensor’s resolution and sensitivity and has attracted widespread attention.The metamaterial is a kind of artificial periodic structure that can enhance the local electromagnetic resonance response, realize sub-wavelength resolution and improve the sensor’s resolution and sensitivity. The terahertz metamaterial sensor provides a new detection method for the field of biosensing, which has the advantages of high sensitivity, fast response speed, and label-free detection. With the rapid development of micro-nano processing technology, the cost of making metamaterial terahertz sensors continues to decrease, which has great potential application value in the field of biomedicine. Research on terahertz sensors based on metamaterials has become a very popular international frontier direction. However, there are no reports on the latest research progress of terahertz metamaterial sensors. Therefore, this paper has collected and sorted out relevant information and reviewed the latest applications of the terahertz metamaterial sensor in various biological detection scenarios, including medical diagnosis, food safety, pesticide detection and so on. Finally, the development and application prospect of Terahertz metamaterials in biosensors are summarized and prospected. This paper will provide an important reference for people to grasp the latest application progress of Terahertz metamaterial biosensors and guide the development and application of Terahertz metamaterial biosensors.

Key words：Terahertz; Metamaterial sensor; Medical diagnosis; Food safety; Pesticide detection

Received: 2020-06-09 Accepted: 2020-10-02

ZTFLH:

O433.1

Corresponding Authors: QI Li-mei E-mail: qilimei1204@163.com

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[1] Bartalini S, De Natale P. Nature Photonics, 2015, 9: 147.
[2] Danciu M, Alexa-Stratulat T, Stefanescu C, et al. Materials, 2019, 12(9): 1519.
[3] Peng Yan, Zhu Yiming, Gu Min, et al. Light: Science and Applications, 2019, 8: 72.
[4] Mittleman D M. Journal of Applied Physics, 2017, 122: 230901.
[5] Han S P, Kim N, Lee W H, et al. Applied Physics Express, 2016, 9(2): 022501.
[6] Akyildiz I F, Jornet J M, Han C. Physical Communication, 2014, 12: 16.
[7] Smith D R, Padilla W J, Vier D C, et al. Physics Review Letters, 2000, 84(18): 4184.
[8] YAN Xin, ZHANG Xing-fang, LIANG Lan-ju, et al(闫昕，张兴坊，梁兰菊，等). Spectroscory and Spectral Analysis(光谱学与光谱分析), 2014, 34(9): 2365.
[9] Al-Naib I. IEEE J. Sel. Top Quant，2017, 23(4): 4700405.
[10] Lee D K, Kang J H, Lee J S, et al. Scientific Reports, 2015, 5: 15459.
[11] Chen Meng, Fan Fei, Shen Si, et al. Applied Optics, 2016, 55: 6471.
[12] Xie Lijuan, Gao Weilu, Shu Jie, et al. Scientific Reports, 2015, 5: 8671.
[13] Geng Zhaoxin, Zhang Xiong, Fan Zhiyuan, et al. Scientific Reports, 2017, 7: 16378.
[14] Bui T S, Dao T D, Dang L H, et al. Scientific Report, 2016, 6: 32123.
[15] Lee D K, Kang J H, Kwon J, et al. Scientific Reports, 2017, 7: 8146.
[16] Perozich J, Kuo I, Wang B, C, et al. European Journal of Biochemistry, 2000, 267(20): 6197.
[17] Liu Weimin, Fan Fei, Chang Shengjiang, et al. Optics Communications, 2017, 405: 17.
[18] Kaczmarek A, Vandenabeele P, Krysko D V. Immunity, 2013, 38(2)：209.
[19] Kamal A, Faazil S, MalikM S. Expert Opinion on Therapeutic Patents, 2014, 24(3): 339.
[20] Zhang Zhang, Ding Hongwei, Yan Xin, et al. Optics Materials Express, 2018, 8: 659.
[21] Pantel K, Brakenhoff R H, Brandt B. Nature Reviews Cancer, 2008, 8(5): 329.
[22] Pantel K, Alix-Panabieres C, Riethdorf S. Nature Reviews Clinical Oncololy, 2009, 6(6), 339.
[23] Zhu Mei, Zhang Lian, Ma Shengqian, et al. Materials Research Express, 2019, 6(4): 045805.
[24] Zhang Rui, Chen Qingming, Liu Kai, et al. IEEE Transactions on Terahertz Science and Technology, 2019, 9(2): 209.
[25] Hassan E M, Mohamed A, DeRosa M C, et al. Sensors and Actuators B: Chemical, 2019, 287: 595.
[26] Keshavarz A, Vafapour Z. IEEE Sensors Journal, 2019, 19: 1519.
[27] Lan Feng, Luo Feng, Mazumder P, et al. Biomedical Optics Express, 2019, 10(8): 3789.
[28] Lee S H, Lee D, Choi M H, et al. Analytical Chemistry, 2019, 91(10): 6844.
[29] Vieira M N N, Lima R A S, De Felice F G. Neuropharmacology, 2018, 136: 160.
[30] Li Dongxia, Lin Shangjun, Hu Fangrong, et al. IEEE Sensors Journal, 2019, 20: 1821.
[31] Zhao Rong, Zou Bin, Zhang Guling, et al. Journal of Physics D: Applied Physics, 2020, 53: 195401.
[32] Al-Antary T M, Shaderma A M, Al-Dabbas M B. Fresen. Environ. Bull., 2019, 28: 370.
[33] Affum A O, Acquaah S O, Osae S D, et al. Science of the Total Environ., 2018, 633: 630.
[34] Xu Wendao, Xie Lijuan, Zhu Jianfei, et al. Carbon, 2019, 141: 247.
[35] Nie Pengcheng, Zhu Dongying，Cui Zijian, et al. Sensors and Actuators B: Chemical, 2019, 307: 127642.
[36] Liu Jianjun. Materials Chemistry and Physics, 2020, 242: 122542.
[37] Baronian K H R. Biosensors and Bioelectronics, 2004, 19(9): 953.
[38] Park S J, Son B H, Choi S J, et al. Optics Express, 2014, 22: 30467.
[39] Jalali-Heravi M, Vosough M. Journal of Chromatography A, 2004, 1024(1-2): 165.
[40] Tang Mingjie, Xia Liangping, Wei Dongshan, et al. Spectrpchimica Acta Part A: Molecular and Biomolecular Spectrocopy, 2020, 228: 117736.
[41] ZHANG Jing-jing(张晶晶). Chinese Science News(中国科学报), 2018.