Abstract：A new system for the determination of dipyridamole with flow injection chemiluminescence was described. It is based on the chemiluminescence reaction of dipyridamole-potassium permanganate with rhodamine B. Tween-80 was found to be an enhancer of the chemiluminescence reaction. A method based on the enhanced chemiluminescence for dipyridamole determination has been developed. The method has high sensitivity, selectivity and good repeatability with a linear concentration range of 5.0×10-8-5.0×10-5 g·mL-1，a detection limit of 1.7×10-8 g·mL-1 and a RSD of 1.1％(n=11, cs=1.0×10-6 g·mL-1).
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