Study on the Inclusion Behavior of p-Sulphonatocalix[4]arene with Acridine by Spectrofluorometric Titrations
ZHOU Yun-you, LU Qin, LIU Chun, SHE Shi-ke, YANG Xu-lai, WANG Lun
Anhui Key Laboratory of Funtional Molecular Solids, Institute of Analytical Science, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China
Abstract：p-sulphonatocalix[4]arene(1)was prepared according to the literature, and spectrofluorometric titrations were performed to investigate the inclusion behavior of (1) and acridine in citrate buffer solution (pH 5.92, 0.1 mol·L-1)at different temperatures. It was found that in definite concentration range, the emission peak of acridine exhibited a slight red shift and the fluorescence intensity decreased when (1) was added. They form stable host-guest complex, and the stoichiometry of the inclusion complex is 1∶1. The stability constants of the inclusion complex at 15.0 ℃, 20.0, 25.0 and 30.0 ℃ were determined as 3.08×105,4.45×104,2.58×104 and 8.90×103, respectively. The thermodynamic parameters of inclusion process, ΔG,ΔH and ΔS, were determined. The experimental results indicated that the inclusion process was an exothermic and enthalpy-driven process. It was found that the stability constants descended when temperature rose. The most probable pattern of the inclusion complex between (1) and acridine was proposed as: acridine partially goes into the cavity of (1), and the protonated N atom and the negatively charged sulphonyl group bond firmly owing to strong electrostatic interaction. With the main contribution of electrostatic interaction and the assistance of Van de Waals and hydrophobic interaction, the host and the guest molecules form 1∶1 supramolecular complex.
Key words：p-sulphonatocalix[4]arene;Acridine;Spectrofluorometric titration;Stability constants of complexation;Electrostatic interaction
周运友，卢琴，刘春，佘世科，杨续来，王伦 . 荧光光谱滴定法研究对磺酸基杯[4]芳烃对吖啶的包结作用[J]. 光谱学与光谱分析, 2006, 26(09): 1627-1630.
ZHOU Yun-you, LU Qin, LIU Chun, SHE Shi-ke, YANG Xu-lai, WANG Lun. Study on the Inclusion Behavior of p-Sulphonatocalix[4]arene with Acridine by Spectrofluorometric Titrations. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(09): 1627-1630.
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