Research on Cells Ablation Characters by Laser Plasma
HAN Jing-hua1, ZHANG Xin-gang2, CAI Xiao-tang3, DUAN Tao4, FENG Guo-ying1*, YANG Li-ming5, ZHANG Ya-jun1, WANG Shao-peng1, LI Shi-wen1
1. College of Electronics & Information Engineering, Sichuan University, Chengdu 610064, China 2. School of Life Sciences, Sichuan University, Chengdu 610064, China 3. West China Second University Hospital, Sichuan University, Chengdu 610041, China 4. Laboratory for Extreme Conditions Matter Properties, Southwest University of Science and Technology, Mianyang 621010, China 5. Chengdu Fine Optical Engineering Research Center, Chengdu 610041, China
Abstract：The study on the mechanism of laser ablated cells is of importance to laser surgery and killing harmful cells. Three radiation modes were researched on the ablation characteristics of onion epidermal cells under: laser direct irradiation, focused irradiation and the laser plasma radiation. Based on the thermodynamic properties of the laser irradiation, the cell temperature rise and phase change have been analyzed. The experiments show that the cells damage under direct irradiation is not obvious at all, but the focused irradiation can cause cells to split and moisture removal. The removal shape is circular with larger area and rough fracture edges. The theoretical analysis found out that the laser plasma effects play a key role in the laser ablation. The thermal effects, radiation ionization and shock waves can increase the deposition of laser pulses energy and impact peeling of the cells, which will greatly increase the scope and efficiency of cell killing and is suitable for the cell destruction.
韩敬华1，张新刚2，蔡晓唐3，段 涛4，冯国英1*，杨李茗5，张亚筠1，王绍朋1，李世文1 . 激光等离子体效应对细胞烧蚀特性研究[J]. 光谱学与光谱分析, 2012, 32(08): 2022-2026.
HAN Jing-hua1, ZHANG Xin-gang2, CAI Xiao-tang3, DUAN Tao4, FENG Guo-ying1*, YANG Li-ming5, ZHANG Ya-jun1, WANG Shao-peng1, LI Shi-wen1 . Research on Cells Ablation Characters by Laser Plasma . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2012, 32(08): 2022-2026.
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