Characterization of Napropamide Enantiomers by CD and Determination of the Enantiomeric Ratios in Water
CHEN Sheng-wen1, CAI Xi-yun1, XI Meng1, ZHANG An-ping1, LIU Wei-ping1, 2*
1. Institute of Environmental Science, Zhejiang University, Hangzhou 310029, China 2. Research Center of Environmental Science, Zhejiang University of Technology, Hangzhou 310032, China
Abstract:The enantiomers of napropamide were separated by normal phase HPLC (HPLC: high performance liqaid Chroatography)with Chiralpak OJ-H column and charactered by circular dichroism. On this basis, a method for the chiral separation and micro-determination of napropamide in water was established. The linearity of calibration curve for racemic mixture was 10-100 ng·mL-1 and the correlation coefficient was 0.99. When 10 μL was injected,the detection limit of racemic mixture was 8 ng·mL-1, and the detection limits of both enantiomers were 4 ng·mL-1.
陈胜文1, 蔡喜运1, 席萌1, 张安平1, 刘维屏1, 2* . 敌草胺对映体圆二色光谱表征及其水体中微量对映体含量测定[J]. 光谱学与光谱分析, 2006, 26(09): 1649-1652.
CHEN Sheng-wen1, CAI Xi-yun1, XI Meng1, ZHANG An-ping1, LIU Wei-ping1, 2* . Characterization of Napropamide Enantiomers by CD and Determination of the Enantiomeric Ratios in Water . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(09): 1649-1652.
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