Studies on Ru(bipy)2dppx2+ as Interacting Mode Spectroscopic Probe of DNA
CHEN Fang1，2, HE Zhi-ke1*
1. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China 2. Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074, China
Abstract：The interacting mode of adriamycin with DNA has been studied by the use of molecular “light switch" complex Ru(bipy)2dppx2+ as a interacting mode spectroscopic probe. The results of the influence of ADM on the fluorescence and Scatchard equation of Ru(bipy)2dppx2+-DNA system indicate that ADM intercalates the base pairs of DNA. Compared with normal DNA interacting mode spectroscopic probe EB, Ru(bipy)2dppx2+ has the advantages of higher sensitivity, lower toxicity, higher stability and simplicity.
陈 芳1，2, 何治柯1*. Ru(bipy)2dppx2+用作核酸作用方式光谱探针研究[J]. 光谱学与光谱分析, 2005, 25(12): 2052-2055.
CHEN Fang1，2, HE Zhi-ke1*. Studies on Ru(bipy)2dppx2+ as Interacting Mode Spectroscopic Probe of DNA . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2005, 25(12): 2052-2055.
