良性与恶性多形性腺瘤组织结构的FTIR光谱研究

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摘要：结合口腔医院临床需要，利用PE公司的Spectrum GX傅里叶变换红外光谱仪，通过对5例良性、4例恶性多形性腺瘤组织的FTIR光谱测试、计算与分析，进行了多形性腺瘤组织结构的FTIR光谱对比研究。测试结果表明： (1)同种性质组织的FTIR光谱表现出了良好的一致性，揭示了吸收峰体现了生物组织的特征红外谱;(2)良性与恶性瘤的FTIR吸收峰峰位及其强度有若干处不同，揭示了恶性肿瘤中蛋白质的酰胺Ⅱ带氢键化程度降低，而脂类的氢键化程度提高;(3)峰高比计算结果表明，良性多形性腺瘤相比，恶性瘤中核酸的含量相对于胶原蛋白的含量增加，脂类的含量相对于蛋白质的含量增加。

关键词：傅里叶变换红外光谱;肿瘤;多形性腺瘤

Abstract：The FTIR(Fourier transform infrared) spectra of benign pleomorphic adenoma tissues and malignant ones were investigated using the spectrometer GX FTIR Spectroscopy. The results indicated that there were infrared spectra difference between the benign adenoma tissues and the malignant ones in some bands. Compared to the benign adenoma tissues,the contents of nucleic acid relative to the collagen protein and the adipose relative to the protein both increase in malignant ones.

Key words：FTIR;Tumor;Pleomorphic adenoma

收稿日期: 2006-03-08 修订日期: 2006-06-16

中图分类号:

O657.3

通讯作者: 刘蒸 E-mail: jpzhu@xjtu.edu.cn

引用本文:

朱京平¹,胡浩屯²,向荣¹,易文辉¹,刘蒸² . 良性与恶性多形性腺瘤组织结构的FTIR光谱研究[J]. 光谱学与光谱分析, 2007, 27(07): 1295-1298.
ZHU Jing-ping¹,HU Hao-tun²,XIANG Rong¹,YI Wen-hui¹,LIU Zheng² . FTIR Analysis of Benign and Malignant Pleomorphic Adenoma Tissues. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(07): 1295-1298.

链接本文:

https://www.gpxygpfx.com/CN/Y2007/V27/I07/1295

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