|
|
|
|
|
|
Extraction of Effective Signal in Non-Invasive Blood Glucose Sensing with Near-Infrared Spectroscopy |
HAN Guang, LIU Rong*, XU Ke-xin |
State Key Laboratory of Precision Measuring Technology and Instruments,Tianjin University,Tianjin 300072,China |
|
|
Abstract Relative measurement of near-infrared (NIR) spectroscopy is of great significance for the high precision detection of human blood glucose concentration in vivo. Although the similar background subtraction and double-beam design are frequently used in the in vitro experiments, they are not suitable for the human body detection because of the complex background variations. Reference measurement based on position is one of the most promising methods to realize in vivo reference measurement. The author proposes differential floating reference measurement method for in vivo reference measurement. The differential floating reference measurement is a universal method. However, it is difficult to determine the radial detection positions and extract the effective information from differential signals in practical use. To solve these problems, differential floating reference based on NAS (Net Analyte Signal)-VIP (Variable Importance in Projection)-SPXY (Sample set Partitioning based on joint X-Y distances)-PLS (Partial Least Square) method is proposed and the feasibility is investigated byin vitro and in vivo experiments, the results shows that the prediction accuracy and precision are improved through this method.
|
Received: 2017-04-17
Accepted: 2017-09-25
|
|
Corresponding Authors:
LIU Rong
E-mail: rongliu@tju.edu.cn
|
|
[1] Yadav J, Rani A, Singh V, et al. Biomedical Signal Processing and Control, 2015, 18: 214.
[2] Amaral C E F, Wolf B. Medical Engineering & Physics, 2008, 30(5): 541.
[3] Min X L, Liu R, Hu Y X, et al. Analytical Methods, 2014, 6(24): 9831.
[4] Min X L, Liu R, Xu K X, et al. Optics & Laser Technology, 2017, 91: 7.
[5] Han G, Yu X Y, Xu K X, et al. Applied Spectroscopy, 2017, 71(9): 2177.
[6] Du Y P, Liang Y Z, Kasemsumran S, et al. Analytical Sciences, 2004, 20(9): 1339.
[7] LI Qing-bo, HUANG Zheng-wei(李庆波,黄政伟). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2014,34(2): 494.
[8] Palermo R N, Short S M, Anderson C A, et al. Journal of Pharmaceutical Innovation, 2012, 7(2): 56.
[9] Zou X B, Zhao J W, Malcolm J W P, et al. Analytica Chimica Acta, 2010, 667(1-2): 14.
[10] Gani W, Limam M. Journal of Statistical Computation & Simulation, 2016, 86(1): 135.
[11] Clarke W L. Diabetes Technol. Ther., 2005, 7(5): 776. |
[1] |
GAO Feng1, 2, XING Ya-ge3, 4, LUO Hua-ping1, 2, ZHANG Yuan-hua3, 4, GUO Ling3, 4*. Nondestructive Identification of Apricot Varieties Based on Visible/Near Infrared Spectroscopy and Chemometrics Methods[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 44-51. |
[2] |
BAO Hao1, 2,ZHANG Yan1, 2*. Research on Spectral Feature Band Selection Model Based on Improved Harris Hawk Optimization Algorithm[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 148-157. |
[3] |
HU Cai-ping1, HE Cheng-yu2, KONG Li-wei3, ZHU You-you3*, WU Bin4, ZHOU Hao-xiang3, SUN Jun2. Identification of Tea Based on Near-Infrared Spectra and Fuzzy Linear Discriminant QR Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3802-3805. |
[4] |
LIU Xin-peng1, SUN Xiang-hong2, QIN Yu-hua1*, ZHANG Min1, GONG Hui-li3. Research on t-SNE Similarity Measurement Method Based on Wasserstein Divergence[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3806-3812. |
[5] |
BAI Xue-bing1, 2, SONG Chang-ze1, ZHANG Qian-wei1, DAI Bin-xiu1, JIN Guo-jie1, 2, LIU Wen-zheng1, TAO Yong-sheng1, 2*. Rapid and Nndestructive Dagnosis Mthod for Posphate Dficiency in “Cabernet Sauvignon” Gape Laves by Vis/NIR Sectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3719-3725. |
[6] |
WANG Qi-biao1, HE Yu-kai1, LUO Yu-shi1, WANG Shu-jun1, XIE Bo2, DENG Chao2*, LIU Yong3, TUO Xian-guo3. Study on Analysis Method of Distiller's Grains Acidity Based on
Convolutional Neural Network and Near Infrared Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3726-3731. |
[7] |
LUO Li, WANG Jing-yi, XU Zhao-jun, NA Bin*. Geographic Origin Discrimination of Wood Using NIR Spectroscopy
Combined With Machine Learning Techniques[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3372-3379. |
[8] |
ZHANG Shu-fang1, LEI Lei2, LEI Shun-xin2, TAN Xue-cai1, LIU Shao-gang1, YAN Jun1*. Traceability of Geographical Origin of Jasmine Based on Near
Infrared Diffuse Reflectance Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3389-3395. |
[9] |
YANG Qun1, 2, LING Qi-han1, WEI Yong1, NING Qiang1, 2, KONG Fa-ming1, ZHOU Yi-fan1, 2, ZHANG Hai-lin1, WANG Jie1, 2*. Non-Destructive Monitoring Model of Functional Nitrogen Content in
Citrus Leaves Based on Visible-Near Infrared Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3396-3403. |
[10] |
HUANG Meng-qiang1, KUANG Wen-jian2, 3*, LIU Xiang1, HE Liang4. Quantitative Analysis of Cotton/Polyester/Wool Blended Fiber Content by Near-Infrared Spectroscopy Based on 1D-CNN[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3565-3570. |
[11] |
HUANG Zhao-di1, CHEN Zai-liang2, WANG Chen3, TIAN Peng2, ZHANG Hai-liang2, XIE Chao-yong2*, LIU Xue-mei4*. Comparing Different Multivariate Calibration Methods Analyses for Measurement of Soil Properties Using Visible and Short Wave-Near
Infrared Spectroscopy Combined With Machine Learning Algorithms[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3535-3540. |
[12] |
KANG Ming-yue1, 3, WANG Cheng1, SUN Hong-yan3, LI Zuo-lin2, LUO Bin1*. Research on Internal Quality Detection Method of Cherry Tomatoes Based on Improved WOA-LSSVM[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3541-3550. |
[13] |
HUANG Hua1, LIU Ya2, KUERBANGULI·Dulikun1, ZENG Fan-lin1, MAYIRAN·Maimaiti1, AWAGULI·Maimaiti1, MAIDINUERHAN·Aizezi1, GUO Jun-xian3*. Ensemble Learning Model Incorporating Fractional Differential and
PIMP-RF Algorithm to Predict Soluble Solids Content of Apples
During Maturing Period[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(10): 3059-3066. |
[14] |
CHEN Jia-wei1, 2, ZHOU De-qiang1, 2*, CUI Chen-hao3, REN Zhi-jun1, ZUO Wen-juan1. Prediction Model of Farinograph Characteristics of Wheat Flour Based on Near Infrared Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(10): 3089-3097. |
[15] |
GUO Ge1, 3, 4, ZHANG Meng-ling3, 4, GONG Zhi-jie3, 4, ZHANG Shi-zhuang3, 4, WANG Xiao-yu2, 5, 6*, ZHOU Zhong-hua1*, YANG Yu2, 5, 6, XIE Guang-hui3, 4. Construction of Biomass Ash Content Model Based on Near-Infrared
Spectroscopy and Complex Sample Set Partitioning[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(10): 3143-3149. |
|
|
|
|