| 光谱学与光谱分析 |
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| Discrimination of Normal and Malignant Gastric Tissues with FTIR Spectroscopy and Principal Component Analysis |
| Peter R Griffiths1, YANG Hu-sheng1，LI Qing-bo2, LING Xiao-feng2, WANG Jian-sheng3, YANG Li-min2, XU Yi-zhuang2, WENG Shi-fu2, WU Jin-guang2* |
1. Department of Chemistry, College of Letters and Sciences, University of Idaho, ID, 83844, USA
2. College of Chemistry and Molecular Engineering，Third Hospital, Peking University, Beijing 100871, China
3. First Hospital of Xi′an Jiaotong University, Xi′an 710061, China |
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Abstract In this paper, the identification of normal and malignant gastric tissues, including 11 cases of cancerous tissues and 10 cases of normal tissues, was investigated using mid-IR spectroscopy and principal component analysis (PCA). The results indicated that the difference between cancerous and normal tissues was found in the first principal component. The IR detection and PCA results are in agreement with the biopsy results. The combination of these two methods might provide a new opportunity for clinical application.
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Received: 2004-02-16
Accepted: 2004-06-26
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Corresponding Authors:
WU Jin-guang
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| Cite this article: |
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Peter R Griffiths,YANG Hu-sheng,LI Qing-bo, et al. Discrimination of Normal and Malignant Gastric Tissues with FTIR Spectroscopy and Principal Component Analysis [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2004, 24(09): 1025-1027.
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| URL: |
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http://www.gpxygpfx.com/EN/Y2004/V24/I09/1025 |
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