Study on Hg2+ Distribution and Speciation in Different Tissues of Rats
SHEN Jin-can1, HUANG Zhi-yong3, ZHUANG Zhi-xia1, 2, WANG Xiao-ru1, 2*, Lee Frank S C2
1. Department of Chemistry, The Key Laboratory of Analytical Sciences of the Ministry of Education, Xiamen University, Xiamen 361005, China 2. First institute Oceanography, S.O.A., Qindao 266061, China 3. College of Bioengineering, Jimei University, Xiamen 361021, China
Abstract：Mercury is one of the important pollutants that threaten people health greatly in environment. The purpose of this paper was to determine mercury distribution and mercury binding proteins in different tissues of rat fed orally with mercuric chloride by ICP-MS and SEC-UV-ICP-MS. The result showed that liver and kidney induced large amount of metallothioneins that was found to bind to mercury, copper and zinc after mercury intake in stomach and intestines. The metallothioneins induced may be prior to combine the mercury so that it would decrease mercury binding with the other proteins that would disable their normal function.
沈金灿1，黄志勇3，庄峙厦1, 2，王小如1, 2*，Lee Frank S C2 . Hg2+在大鼠组织器官中的分布及其存在形态研究[J]. 光谱学与光谱分析, 2005, 25(10): 1688-1692.
SHEN Jin-can1, HUANG Zhi-yong3, ZHUANG Zhi-xia1, 2, WANG Xiao-ru1, 2*, Lee Frank S C2 . Study on Hg2+ Distribution and Speciation in Different Tissues of Rats . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2005, 25(10): 1688-1692.
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