Effect of High Performance Liquid Chromatographic Instrument System on the Analysis of Erythromycin A Oxime
SUN Jing-guo1, 2，YAO Guo-wei1，OU Yu-xiang3
1. School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081, China 2. Chemistry College of Hebei Normal University, Shijiazhuang 050091, China 3. School of Material Science and Engineering，Beijing Institute of Technology, Beijing 100081, China
Abstract：A HPLC chromatography for the determination of erythromycin A oxime and relative compounds was studied, amd the effect of chromatography systems including a HITACHI L-7100, a Shimadzu LC-6A, a WatersTM 474 and relative columns was analyzed. It was revealed that different HPLC apparatus and columns have obvious impact on the peak separation and retention time under the general chromatographic condition. The suitable chromatographic conditions for several different chromatography systems were summarized with good linear relationship，which is very significant to the quality control of erythromycin A oxime and relative compounds.
Key words：HPLC;Chromatographic Instrument;Erythromycin A oxime
孙京国1,2，姚国伟1，欧育湘3 . 高效液相色谱仪器系统对红霉素肟分析的影响 [J]. 光谱学与光谱分析, 2004, 24(09): 1148-1150.
SUN Jing-guo1, 2，YAO Guo-wei1，OU Yu-xiang3 . Effect of High Performance Liquid Chromatographic Instrument System on the Analysis of Erythromycin A Oxime . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2004, 24(09): 1148-1150.
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