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SPECTROSCOPY AND SPECTRAL ANALYSIS  2016, Vol. 36 Issue (04): 1230-1234    DOI: 10.3964/j.issn.1000-0593(2016)04-1230-05
光谱学与光谱分析 |
TOF-SIMS Study of Mannitol and Cordycepin in Cordyceps Sinensis
LI Zhan-ping1, Noriaki Sanada2, SUN Su-qin1
1. Analysis Center, Tsinghua University, Beijing 100084, China
2. ULVAC-PHI Inc. 370 Enzo, Chigasaki, Kanagawa, 253-8522, Japan
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Abstract  Cordyceps sinensis is a well-known traditional Chinese medicine; it is also called DongChongXiaCao (winter worm summer grass) in Chinese. Mannitol and cordycepin, the most important two pharmacological active components of cordyceps sinensis, were studied with TOF-SIMS. This Study was focused on the chemical information including 251 amu mass peak. Based on high mass resolution of TOF-SIMS analysis, the fragment ions of 251 and 252 amu detected in Cordyceps sinensis may not be the molecular ion M+ and/or[M+H]+ of cordycepin, which ispossiblely the root cause of the argument in the study of cordycepin in published papers .It could be a basis for further study of cordycepin components of cordyceps sinensis in the future. The 181amu mass peak of minus ion in mannitol was also studied in detail and was certified to be a reliable evidence of mannitol. This research shows that TOF-SIMS has been proven as an effective method in the study of cordyceps sinensis.
Key words:Cordyceps sinensis;Mannitol;Cordycepin;TOF-SIMS
Received: 2014-08-04     Accepted: 2014-12-22    
ZTFLH:  R282.5  
Corresponding Authors: LI Zhan-ping     E-mail: zhanpingli@mail.tsinghua.edu.cn
Cite this article:   
LI Zhan-ping,Noriaki Sanada,SUN Su-qin. TOF-SIMS Study of Mannitol and Cordycepin in Cordyceps Sinensis [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2016, 36(04): 1230-1234.
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https://www.gpxygpfx.com/EN/10.3964/j.issn.1000-0593(2016)04-1230-05     OR      https://www.gpxygpfx.com/EN/Y2016/V36/I04/1230