Abstract：The authors acquired Raman spectra of three kinds of estrogen by portable Raman spectrometer, including 17β-estradiol (C18H24O2), estriol (C18H24O3) and diethylstilbestrol (C18H20O2). Analysis, comparison and simulation of the three estrogens were carried out, and the diethylstilbestrol Raman spectrum, which is hard to detect, was acquiredt by surface enhanced Raman scattering technology. Results show that Raman technique can detect 17β-estradiol (C18H24O2), estriol (C18H24O3) and diethylstilbestrol (C18H20O2) quickly and accurately.
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