| 光谱学与光谱分析 |
|
|
|
|
|
| Studies on the Interaction of the Metal Complex of Hydrazide of Podophyllic Acid with DNA |
| WANG Ping-hong1, ZHANG Qi1*, WANG Liu-fang2, SONG Yu-min3, QU Jian-qiang2, LIU Ying-qian2 |
1. Province Key Laboratory of Refined Chemistry, Hainan University, Haikou 570228, China
2. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China
3. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China |
|
|
|
|
Abstract The interaction between the metal complex of hydrazide of podophyllic acid and calf thymus (CT) DNA was studied by using absorption spectra, fluorescence spectra and DNA heat denaturation. It was found that the intensity of the maximal absorption peaks from absorption spectra is weakened in the presence of the metal complex of hydrazide of podophyllic acid compared with that in the absence of the metal complex. All the experimental results show that the intercalation mode was proved to exist between HDPP-Ni complexes and CT DNA.
|
|
Received: 2005-03-19
Accepted: 2005-08-20
|
|
|
|
Corresponding Authors:
ZHANG Qi
|
|
| Cite this article: |
|
WANG Ping-hong,ZHANG Qi,WANG Liu-fang, et al. Studies on the Interaction of the Metal Complex of Hydrazide of Podophyllic Acid with DNA[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(05): 941-943.
|
|
|
|
| URL: |
|
https://www.gpxygpfx.com/EN/Y2006/V26/I05/941 |
[1] Marmur J. J. Mol. Biol., 1961, 3: 208.
[2] Reichmann M E, Rice S A, Thomas C A, et al. J. Am. Chem. Soc., 1954, 76: 3047.
[3] Kumar C V, Asumcion E H, J. Am. Chem. Soc., 1993, 115: 8547.
[4] Chaires J B. Biochem., 1986, 25: 8436.
[5] YANG Pin(杨 频). Introduction of Inorganic Chemistry(生物无机化学导论). Xi’an: Xi’an Jiaotong University Press(西安: 西安交通大学出版社), 1991. 155.
[6] LI Lai-sheng, HUANG Wei-dong, et al(李来生, 黄伟东，等). Acta Chimica Sinica(化学学报), 1999, 57: 572.
|
| [1] |
QIU Bo, LIU Jin-feng, LIU Yao-chi, YANG Zhao-guang, LI Hai-pu* . Ultraviolet-Visible Spectrometry Analysis of Insoluble Xanthate Heavy Metal Complexes [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2014, 34(11): 3025-3029. |
| [2] |
LIU Ju-tao, LU Yan-fei, FAN Sheng-di. Synthesis, Spectroscopic Characterization and Antitumoral Activities of Cyclopentadienylvanadium Derivatives of Polyoxotungstates [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2012, 32(09): 2512-2514. |
| [3] |
GAO Xue-xi1, WANG Wen-jun1*, LIU Yun-long1, LI Da-cheng2, ZHANG Bing-yuan1, XU Jian-hua3 . Studies on Fluorescence Properties of a Novel Acylhydrazone Ligands and Its Sn Metal Complexes [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2012, 32(01): 147-151. |
| [4] |
WU Cheng-ke1, DONG Qiu-peng1，2, ZHANG Hong1, XIONG Cen1, WU Xiu-li1, LING Lian-sheng1* . Spectral Study on the Interaction of [Cu(DPPZ)(L-Ser)]+ Complex with DNA and Its Analytical Application [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2011, 31(04): 1057-1060. |
| [5] |
TONG Chang-lun, ZHANG Xiao-xiang. Study on the Interaction of Ofloxacin and Levofloxacin with DNA [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2010, 30(02): 481-485. |
| [6] |
HUANG Zi-yang1, 2, HUANG Jian-dong1, CHEN Nai-sheng1, HUANG Jin-ling1* . Study on UV-Vis Absorption Spectra and Fluorescence Emission Spectra of Sixteen Tetra-Substituted Metallophthalocyanine Complexes [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2009, 29(05): 1354-1357. |
| [7] |
DUAN Yun-qing1,2,MIN Shun-geng1* . Study of the Interaction Mechanism between Brodifacoum and DNA by Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2009, 29(04): 999-1003. |
| [8] |
JIANG Xin1,2,WU Yi-qun1,3*,HE Chun-ying1. Synthesis and Spectra of Novel Metal Complexes of Multi-Nitrogen Heterocyclic Ligand[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2008, 28(11): 2511-2514. |
| [9] |
MA Jing2, MENG Qing-xiang1, REN Li-ping1*, ZHANG Tao2, MU Hao-jie2. Study on the Interaction of Atrazine and ct-DNA by Fluorescence Probe Technique[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2008, 28(09): 2122-2125. |
| [10] |
LI Hua1,YU Yan-ying1*,HU Xin1,CAO Shu-wen1,2. Research on the Interactions between Genistein and Its Glucosides with DNA[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2008, 28(08): 1905-1909. |
| [11] |
YU Yan-ying1,LI Hua1,HU Xin1,CAO Shu-wen2*. Research on the Interaction of Cr(Ⅲ) Complex of Genistein with DNA[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2008, 28(07): 1587-1591. |
| [12] |
YANG Wu,GAO Qi-kuan,LU Xiao-lin,WU Jin-xiu. Study on the Interactions of Eu(Ⅲ) Complex of O-(Thioxanthone-[2]-yl)-Oxyacetic Acid with DNA[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2008, 28(02): 366-369. |
| [13] |
WU Shan-shan1,ZHANG Yin-feng2,DU Jin-feng1,ZHANG Qi1*, YUAN Wen-bing1,GU Hai-bo1. Synthesis of Sulfur-Contained D(+)-Glucosamine Metal Complexes and Interaction with DNA and Serum Albumin[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2008, 28(02): 374-379. |
| [14] |
WANG Xiao-li1,2,BIAN Zhan-xi1*,WANG Xi-gui2. The IR Spectra of Complexes of N-(Phenyl, Ferrocenyl)Methyl-β-Hydroxyethylamine with Ni(Ⅱ), Cu(Ⅱ), Zn(Ⅱ), Cd(Ⅱ) and Hg(Ⅱ)[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(11): 2221-2223. |
| [15] |
DING Chun-mei,YUE Wen-jin,SU Yun,LI Guo-yan,GUO Li,CHEN Liang. Preparation and Spectral Analysis of Coordination Compounds of Chitosan with Ce(Ⅲ)，Zr(Ⅳ)，Pb(Ⅱ) and Cd(Ⅱ)[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(06): 1185-1187. |
|
|
|
|
