|
|
|
|
|
|
Synthesis and Spectroscopic Characterizations of the Mono- and Bimolecular Iron(Ⅲ) Complexes by the Interaction With Tris Buffer in Neutralized Media: Biological and Morphological Investigations |
Jehan Y Al-Humaidi1, Foziah A Al-Saif1, Dalal N Binjawhar1, Salha E Alotaibi1,Moamen S Refat2,3* |
1. Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia
2. Department of Chemistry, Faculty of Science, Taif University, Al-Haweiah 21974, Taif, Saudi Arabia
3. Department of Chemistry, Faculty of Science, Port Said University, Port Said, Egypt |
|
|
Abstract The reaction of iron(Ⅲ) anions, FeCl3 and Fe2(SO4)3 with tris(hydroxymethyl) aminomethane (Tris) in a 1∶2 molar ratio affords the new coordination compounds NH4[Fe2(Tris)2(H2O)4(SO4)] (Ⅰ) and NH4[Fe(Tris)2(H2O)2] (Ⅱ). These compounds were characterized by elemental analysis, and their molecular structures were determined by spectroscopic methods (infrared and electronic spectra), magnetic susceptibility, and molar conductivity measurements, and further corroborated by thermo gravimetric analysis and its differential (TGA/DrTGA). According to the experimental data, the complexes can be characterized in the solid state as mono- and binuclear, with a distorted octahedral stereochemistry. The distorted octahedral stereochemistry adopted by the complexes was confirmed by the magnetic susceptibility measurement of NH4[Fe2(Tris)2(H2O)4(SO4)], which consists of a six-coordinate iron atoms in a distorted octahedral environment constructed from four O atoms (two Tris molecules), two O atoms from the loosely associated SO4 coordinated ligand, and O, N of second Tris molecule with occupying by four oxygen atoms of coordinated water molecules. Regarding, NH4[Fe(Tris)2(H2O)2] complex the mono iron atom is surrounded by six oxygen atoms as four by two Tris molecules and two coordinated water molecules in axial form. Antibacterial and anticancer activities of the complexes were studied and the complexes were screened against bacteria, colorectal adenocarcinoma (Caco-2) and breast cancer (Mcf-7) cell lines.
|
Received: 2020-02-16
Accepted: 2020-06-02
|
|
Corresponding Authors:
Moamen S Refat
E-mail: msrefat@yahoo.com
|
|
[1] Albishri H M, Marwani H M, Arab. J. Chem., 2016,9:S252.
[2] El-Dissouky A, Khalil T E, Elbadawy H A, et al. J. Mol. Struct., 2020,1200:127066.
[3] Lundblad R L,Macdonald F. Preparation of Buffers for Use in Enzyme Studies: G. Gomori, Handbook of Biochemistry and Molecular Biology, CRC Press, 2010. 739.
Brignac P J, Jr Celine Mo. Analytical Chemistry, 1975,47(8):1465.
[4] Bjerrum J. Metal Ammine Formation in Aqueous Solution. Haase P & Son, Copenhagen, 1941. 36.
Huisman T H, Dozy A M. J. Chromatography A, 1965,19:160.
[5] Hanlon D P, Watt D S, Westhead E W. Analytical Biochemistry, 1966,16:225.
[6] Colombo M F, Austrilino L, Nascimento O R, et al. Can. J. Chem.,1987,65:821.
[7] Bubb W A, Berthon H A, Kuchel P W. Bioorg. Chem., 1995,23:119.
[8] Kallet R H, Jasmer R M, Luce J M, et al. Am. J. Respir. Crit. Care Med., 2000,161:1149.
[9] Odabaşoğlu M, Albayrak C, Büyükgüngör O, et al. Acta Cryst.,2003,C59:o616.
[10] Chumakov Y M, Antosyak B Y, Mazus M D, et al. Kristallografiya Almeza, 2003, 45: 1025.
[11] Asgebom G, Sreedhara A, Rao C P. Polyhedron,1995,14(13-14):1873.
[12] Tatar L, Nazır H, Gümüşer M, et al. Z. Kristallogr., 2005, 220: 639.
[13] Bauer A W, Kirby W A, Sherris C, et al. Am. J. Clin. Pathology, 1996, 45: 493.
[14] Repetto G, del Peso A, Zurita J L. Neutral Red Uptake Assay for the Estimation of Cell Viability/Cytotoxicity, Nature Protocols, 2008.
[15] El-Habeeb A A, Refat M S. J. Mol. Struct., 2019,1175:65.
[16] Mikhaylova Y, Adam G, Häussler L, et al. J. Mol. Struct., 2006,788:80.
[17] Yin H, Chen S W. Inorg. Chim. Acta, 2006,359:3330.
[18] Sui Y, Zeng X, Fang X, et al. J. Molecular Catalysis A: Chemical, 2007, 270: 61.
[19] Nakamoto K. Infrared and Raman Spectra of Inorganic and Coordination Compounds, Fourth ed., Wiley, New York, 1986.
[20] Lever A B P. Electronic Spectra of dn Ions Inorganic Electronic Spectroscopy. 2nd Ed. 1984.
[21] Cotton F A, Wilkinson G. The Element of First Transition Series Advanced Inorganic Chemistry. 3rd Ed,1992.
[22] Cullity B D, Stock S R. Elements of X-Ray Diffraction, 3rd ed. New York: Prentice Hall,2001. 389. |
[1] |
XU Qi-lei, GUO Lu-yu, DU Kang, SHAN Bao-ming, ZHANG Fang-kun*. A Hybrid Shrinkage Strategy Based on Variable Stable Weighted for Solution Concentration Measurement in Crystallization Via ATR-FTIR Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(05): 1413-1418. |
[2] |
KAN Yu-na1, LÜ Si-qi1, SHEN Zhe1, ZHANG Yi-meng1, WU Qin-xian1, PAN Ming-zhu1, 2*, ZHAI Sheng-cheng1, 2*. Study on Polyols Liquefaction Process of Chinese Sweet Gum (Liquidambar formosana) Fruit by FTIR Spectra With Principal Component Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(04): 1212-1217. |
[3] |
YAN Li-dong1, ZHU Ya-ming1*, CHENG Jun-xia1, GAO Li-juan1, BAI Yong-hui2, ZHAO Xue-fei1*. Study on the Correlation Between Pyrolysis Characteristics and Molecular Structure of Lignite Thermal Extract[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(03): 962-968. |
[4] |
LI Zong-xiang1, 2, ZHANG Ming-qian1*, YANG Zhi-bin1, DING Cong1, LIU Yu1, HUANG Ge1. Application of FTIR and XRD in Coal Structural Analysis of Fault
Tectonic[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(02): 657-664. |
[5] |
CHENG Xiao-xiao1, 2, LIU Jian-guo1, XU Liang1*, XU Han-yang1, JIN Ling1, SHEN Xian-chun1, SUN Yong-feng1. Quantitative Analysis and Source of Trans-Boundary Gas Pollution in Industrial Park[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(12): 3762-3769. |
[6] |
ZHANG Hao1, 2, HAN Wei-sheng1, CHENG Zheng-ming3, FAN Wei-wei1, LONG Hong-ming2, LIU Zi-min4, ZHANG Gui-wen5. Thermal Oxidative Aging Mechanism of Modified Steel Slag/Rubber Composites Based on SEM and FTIR[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(12): 3906-3912. |
[7] |
CHEN Jing-yi1, ZHU Nan2, ZAN Jia-nan3, XIAO Zi-kang1, ZHENG Jing1, LIU Chang1, SHEN Rui1, WANG Fang1, 3*, LIU Yun-fei3, JIANG Ling3. IR Characterizations of Ribavirin, Chloroquine Diphosphate and
Abidol Hydrochloride[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(07): 2047-2055. |
[8] |
MA Fang1, HUANG An-min2, ZHANG Qiu-hui1*. Discrimination of Four Black Heartwoods Using FTIR Spectroscopy and
Clustering Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(06): 1915-1921. |
[9] |
ZHANG Dian-kai1, LI Yan-hong1*, ZI Chang-yu1, ZHANG Yuan-qin1, YANG Rong1, TIAN Guo-cai2, ZHAO Wen-bo1. Molecular Structure and Molecular Simulation of Eshan Lignite[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(04): 1293-1298. |
[10] |
WANG Fang-fang1, ZHANG Xiao-dong1, 2*, PING Xiao-duo1, ZHANG Shuo1, LIU Xiao1, 2. Effect of Acidification Pretreatment on the Composition and Structure of Soluble Organic Matter in Coking Coal[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(03): 896-903. |
[11] |
HU Chao-shuai1, XU Yun-liang1, CHU Hong-yu1, CHENG Jun-xia1, GAO Li-juan1, ZHU Ya-ming1, 2*, ZHAO Xue-fei1, 2*. FTIR Analysis of the Correlation Between the Pyrolysis Characteristics and Molecular Structure of Ultrasonic Extraction Derived From Mid-Temperature Pitch[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(03): 889-895. |
[12] |
YANG Jiong1, 2, QIU Zhi-li1, 4*, SUN Bo3, GU Xian-zi5, ZHANG Yue-feng1, GAO Ming-kui3, BAI Dong-zhou1, CHEN Ming-jia1. Nondestructive Testing and Origin Traceability of Serpentine Jade From Dawenkou Culture Based on p-FTIR and p-XRF[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(02): 446-453. |
[13] |
HE Xiong-fei1, 2, HUANG Wei3, TANG Gang3, ZHANG Hao3*. Mechanism Investigation of Cement-Based Permeable Crystalline Waterproof Material Based on Spectral Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2021, 41(12): 3909-3914. |
[14] |
ZHOU Jing1,2, ZHANG Qing-qing1,2, JIANG Jin-guo2, NIE Qian2, BAI Zhong-chen1, 2*. Study on the Rapid Identification of Flavonoids in Chestnut Rose (Rosa Roxburghii Tratt) by FTIR[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2021, 41(10): 3045-3050. |
[15] |
Samy M. El-Megharbel*,Moamen S. Refat. In First Time: Synthesis and Spectroscopic Interpretations of Manganese(Ⅱ), Nickel(Ⅱ) and Mercury(Ⅱ) Clidinium Bromide Drug Complexes[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2021, 41(10): 3316-3320. |
|
|
|
|