Study on Transient Absorption Spectrum of Tungsten Nanoparticle with HepG2 Tumor Cell
CAO Lin1, SHU Xiao-ning1, LIANG Dong1, WANG Cong2
1. School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China 2. The Hong Kong University of Science & Technology, Hong Kong, China
Abstract：Significance of this study lies in tungsten nano materials can be used as a preliminary innovative medicines applied basic research .This paper investigated the inhibition of tungsten nanoparticles which effected on human hepatoma HepG2 cells by MTT. The authors use transient absorption spectroscopy (TAS) technology absorption and emission spectra characterization of charge transfer between nanoparticles and tumor cell. The authors discussed the role of the tungsten nanoparticles in the tumor early detection of the disease and its anti-tumor properties. In the HepG2 experiments system,100～150 μg·mL-1 is the best drug concentration of anti-tumor activity which recact violently within 6 hours and basically completed in 24 hours. The results showed that transient absorption spectroscopy can be used as tumor detection methods and characterization of charge transfer between nano-biosensors and tumor cells. Tungsten nanoparticles have potential applications as anticancer drugs.
曹 林1，舒晓宁1，梁 栋1，王 聪2 . 钨系纳米颗粒与HepG2肿瘤细胞作用的瞬态吸收谱研究 [J]. 光谱学与光谱分析, 2014, 34(07): 1914-1916.
CAO Lin1, SHU Xiao-ning1, LIANG Dong1, WANG Cong2 . Study on Transient Absorption Spectrum of Tungsten Nanoparticle with HepG2 Tumor Cell . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2014, 34(07): 1914-1916.
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