Ratio Spectrophotometry and Its Application to Assay of Compound
Pharmacy Preparations
HUANG Xi-ru1, CAI Yong-mei2, TAI Yan1, CAO Dong1
1. Department of Analytical Chemistry, the School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang 050017, China 2. Hengshui Pharmaceutical Inspection Institute, Hengshui 053000, China
Abstract：The present paper is to study ratio spectrophotometry for its application to the assay of compound pharmacy preparations. According to the feature of ratio spectra, the wavelength pair was selected at the peak point or valley point of ratio spectra to establish ratio spectrophotometry for the determination of Co-Chlorzoxazone tablet and injection of caffeine and sodium benzoate. The average recoveries and relative standard deviations for Chlorzoxazone and paracetamol were 100.0% and 1.28%, and 100.0% and 0.84%, respectively; the average recoveries and relative standard deviations for caffeine and sodium benzoate were 99.98% and 0.70%，and 99.91% and 0.78%, respectively. It is concluded that as long as the ratio spectra exhibit at least one peak and one valley, the results are satisfactory.
Key words：Ratio spectrophotometry;Co-Chlorzoxazone tablet;Injection of caffeine and sodium benzoate
黄喜茹1，蔡永梅2，台 燕1*，曹 冬1 . 比值光谱法在复方药物制剂分析中的应用研究[J]. 光谱学与光谱分析, 2005, 25(04): 620-623.
HUANG Xi-ru1, CAI Yong-mei2, TAI Yan1, CAO Dong1 . Ratio Spectrophotometry and Its Application to Assay of Compound
Pharmacy Preparations. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2005, 25(04): 620-623.
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