Qualitative and Quantitative Analyses of Some Saccharides by THz-TDS
MA Xiao-jing1,2, ZHAO Hong-wei1*, LIU Gui-feng1, JI Te1, ZHANG Zeng-yan1, DAI Bin2
1. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China 2. College of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832003, China
Abstract：Terahertz (THz) radiation lies between the infrared and microwave range of the electromagnetic spectrum. Absorption spectrum in the THz range provides rich information about structure and weak interactions of biomolecules. THz absorption spectra of D-(-)-ribose, D-glucose, α-lactose monohydrate and β-lactose were measured by terahertz time-domain spectroscopy (THz-TDS) in the frequency range of 0.3-1.6 THz at room temperature. The experimental results show that different saccharides have distinct THz absorption features, which suggests that THz-TDS is highly sensitive to molecular structures and components. Quantitative analysis of the mixtures of two to four saccharides was studied by linear regression with relative error less than 7.2%. The reasons for the relative error were discussed. The results demonstrate that THz-TDS is a promising and efficient method for both qualitative and quantitative analyses for pharmaceutical identification and biomolecular detection.
Key words：THz-TDS;Characteristic spectrum;Saccharides;Qualitative and quantitative analyses
马晓菁1,2，赵红卫1*，刘桂锋1，吉 特1，张增艳1，代 斌2 . 多种糖混合物的太赫兹时域光谱定性及定量分析研究[J]. 光谱学与光谱分析, 2009, 29(11): 2885-2888.
MA Xiao-jing1,2, ZHAO Hong-wei1*, LIU Gui-feng1, JI Te1, ZHANG Zeng-yan1, DAI Bin2 . Qualitative and Quantitative Analyses of Some Saccharides by THz-TDS. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2009, 29(11): 2885-2888.
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