Determination of 27 Inorganic Elements in Limonium bicolor by ICP-MS Using Microwave Digestion for Sample Preparation
WANG Bin1, 2, XU Yin-feng1, LI Guo-qiang2*, GUAN Hua-shi2
1. School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316000, China 2. School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
Abstract：An inductively coupled plasma mass spectrometry (ICP-MS) for determination of the contents of 27 inorganic elements in Limonium bicolor after microwave digestion of the sample was developed. The accuracy of the method was evaluated by the analysis of corresponding inorganic elements in standard reference materials (GBW 07605), and matrix effect and signal drift were compensated by using the internal standard elements (Ge, In and Bi). By applying the proposed method, the contents of 27 inorganic elements in Limonium bicolor collected from Dongying (Shandong Province of China) were determined. The precision of measurement ranges from 1.5% to 9.7% in terms of relative standard deviation. The recoveries and the limits of detection are in the range of 92.4%-107.2% and 0.002-0.081 μg·L-1, respectively. It is indicated that the proposed method has the advantages of simplicity, speediness and sensitivity. The results showed that the Limonium bicolor are rich in major elements Na, K, Ca and Mg and trace elements Fe, Mn, Zn, Cr and Cu. This paper provides scientific basis for deeply studying the relation between the inorganic elements and the drug effects of Limonium bicolor.
Key words：Limonium bicolor;Inorganic element;Inductively coupled plasma mass spectrometry (ICP-MS);Microwave digestion
王 斌1, 2，徐银峰1，李国强2*，管华诗2 . 微波消解/ICP-MS法测定二色补血草中27种元素[J]. 光谱学与光谱分析, 2009, 29(11): 3138-3140.
WANG Bin1, 2, XU Yin-feng1, LI Guo-qiang2*, GUAN Hua-shi2 . Determination of 27 Inorganic Elements in Limonium bicolor by ICP-MS Using Microwave Digestion for Sample Preparation . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2009, 29(11): 3138-3140.
[1] ZHANG Lian-ru, CHEN Ke-lin, LI Ni, et al(张连如, 陈喀林, 李 妮, 等). Chemical Journal of Chinese Universities(高等学校化学学报), 2004, 25(11): 2034. [2] ZHU Rong, GUO Liang-hui, CHEN Ji-jun, et al(朱 蓉, 郭梁惠, 陈纪军, 等). Chinese Traditional and Herbal Drugs(中草药), 1991, 22(9): 390. [3] WANG Bing-wen, ZHU Rong, SHEN Si-qing, et al(王秉文, 朱 蓉, 沈四清, 等). Chinese Journal of Xi’an Medical University(西安医科大学学报), 1994, 15(1): 59. [4] Chaung S S, Lin C C, Lin J, et al. Phytotherapy Research, 2003, 17(7): 784. [5] Yamashiro S, Noguchi K, Matsuzaki T, et al. Pharmacology, 2003, 67(3): 128. [6] Aniya Y, Miyagi C, Nakandakari A, et al. Phytomedicine, 2002, 9(3): 239. [7] Asen S, Plimmer J. Phytochemistry, 1972, 11(8): 2601. [8] Ross S A, Bishay D W. Herba Polonica, 1984, 30(2): 91. [9] Lin L C, Kuo Y C, Chou C J. Planta Medica, 2000, 66(4): 333. [10] Bashir A K, Abdalla A A, Wasfi I A, et al. International Journal of Pharmacognosy, 1994, 32(4): 366.
