Abstract:The interaction of alginic sodium diester (ASD) and azur A (AA) was studied by absorption spectra. The influence of pH and the molar ratio of AA/ASD on the spectra was investigated. The maximum binding number (N=168) and the binding equilibrium constant (K=3.25×106) of the alginic sodium diester and azur A were obtained by the theoretical model. The new method for the determination of ASD was developed by the formation of ASD-AA ion-association complex that caused the fading of the AA. The detection limit is 0.009 μg·mL-1. The method has the advantages of simplicity, stable system, good accuracy and selectivity, and was applied to the determination of alginic sodium diester in tablets with satisfactory results.
Key words:Alginic sodium diester;Azur A;Spectrometry;Maximum binding number
刘永明,李桂芝,潘飞. 藻酸双酯钠与天青A相互作用机理的研究与应用[J]. 光谱学与光谱分析, 2007, 27(02): 317-320.
LIU Yong-ming, LI Gui-zhi, PAN Fei. Study on the Interaction between Alginic Sodium Diester and Azur A and the Application . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(02): 317-320.
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