1. Department of Biomedical Engineering and Scientific Instrument, Tianjin University, Tianjin 300072, China 2. Department of Laser Medicine, Chinese PLA General Hospital, Beijing 100853, China
Abstract:To measure and analyze the spectrum of a small skin region for laser therapy of port wine stain is very useful for clinical doctor to understand the optical characters of patient’s pigmented skin, to adjust the output parameters of lasers and then to improve the therapy effects. Based on the analysis of the forming mechanism of port wine stains and clinical operation of the disease, the present paper presents an automatic spectral measurement and analysis system for port wine stain therapy. It can accomplish the spectral detection in the range from 380 to 780 nm, with a spectral resolution of 1 nm. Experiments were performed for patients with various age and pigment diseases; finally, some influencing factors and relevant solutions are enumerated and discussed.
Key words:Port wine stain;Spectral measurement;Laser therapy;Small skin region
[1] LI Wei, LI Ming-shan, GUO Guang-zhao, et al(李 伟,李明山,郭光照,等). Chinese Journal of Plastic Surgery(中华整形外科杂志), 2002, 18(2): 111. [2] YUE Xue-zuang, ZHU Wen-yuan. J. Clin. Dermatol., 2003, 32(9): 554. [3] Haeghen Y V, Philips Wilfried, et al. IEEE Trans. on Medical Imaging, 2000, 19(7): 755. [4] Jung Byungjo, Choi Bernard, Durdin Anthony J. Laser in Surgery and Medicine, 2004, 34: 174. [5] ZHENG Yong-mei, LIANG Lu-guang, ZHANG Tie-qiang(郑咏梅,梁路光,张铁强). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2003,23(1): 25. [6] Haeghen Y V, Philips Wilfried, Lemahieu Ignace, et al. IEEE Transactions on Medical Imaging, 2000, 19(7): 755. [7] Shriver Mark D, Parra Esteban J. American Journal of Physical Anthropology, 2000, 112: 17.