1.中国药科大学分析化学教研室，江苏 南京 210009 2.药物质量与安全预警教育部实验室，江苏 南京 210009 3.Unite de Recherche INSERM 602，GroupeHospitalier Paul Brousse，12 avenue Paul Vaillant Couturier，94807 Villejuif Cedex France
Preparation of Lomefloxacin-Tb3+ Nanoparticles Modified by PVP via Microwave-Assistance and Its Properties of Fluorescence
HE Hua1,2,YE Hai-ying1,LIU Xuhui3
1. Division of Analytical Chemistry，China Pharmaceutical University，Nanjing 210009, China 2. Key Laboratory of Drug Quality Control and Pharmacovigilance, China Pharmaceutical University, Ministry of Education，Nanjing 210009, China 3. Unite de Recherche INSERM 602，GroupeHospitalier Paul Brousse，12 Avenue Paul Vaillant Couturier，94807 Villejuif Cedex France
Abstract：Polyvinylpyrrolidone(PVP)-modified LFLX-Tb3+ nanoparticles were prepared by microwave radiation method. The obtained products were characterized by means of SEM, FTIR and fluorescence spectra. The surface-modified LFLX-Tb3+ nanoparticles showed a narrow size distribution and enhanced luminescence property compared with that of the unmodified ones. These results were attibuted to the surface passivation of the LFLX-Tb3+ nanoparticles by the PVP molecules. It is confirmed that the addition dosage of PVP is an important factor in the preparation of the LFLX-Tb3+ nanoparticles. The reasons for luminescence enhancement were discussed.
Key words：Microwave irradiation;PVP/LFLX-Tb3+LFLX-Tb3+;Nanoparticles;Adsorption;Fluorescence;Charge transfer
何华1,2,叶海英1,LIU Xuhui3. PVP/洛美沙星-铽纳米粒子微波合成及其荧光特性研究[J]. 光谱学与光谱分析, 2007, 27(06): 1164-1167.
HE Hua1,2,YE Hai-ying1,LIU Xuhui3. Preparation of Lomefloxacin-Tb3+ Nanoparticles Modified by PVP via Microwave-Assistance and Its Properties of Fluorescence . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(06): 1164-1167.
[1] Grisaru H, Palchik O, Gedanken A, et al. Inorg. Chem., 2003, 42(22): 7148. [2] Shanmugasundaram M, Manikandan S, Raghunathan R. Tetrahedron, 2002, 58(5): 997. [3] Masaaki T, Koichiro O, Seijiro M. Tetrahedron Letters, 2003, 44(51): 9201. [4] Sudhir K, Tulsi M. Chem. Phys. Lett., 2003, 370: 83. [5] Sun Y, Gates B, Mayers B, et al. Nano. Lett., 2002, 2: 165. [6] Kopeikin V V, Valueva S V, Kipper A I. Polymer Science Series A, 2003, 45: 374. [7] Chandler Robin R, Coffer L. J. Phys. Chem., 1993, 97: 9767. [8] Qian X F，Yin J，Fang S. J. Mater. Char., 2001，11: 2504. [9] Sooklal K, Harms L H，Ploehn H J, et al. Adv. Mater., 1998，10: 1083. [10] HE Hua，YE Hai-ying，DAI Li，et al (何 华，叶海英 , 戴 丽, 等). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2006，26(3)：480. [11] Rosendo A, Hores M, Aroyo R. Materials Lett., 2003, 57: 2885. [12] QI Xue-yong，HE Hua，GU Fei，et al(戚雪勇，何 华，顾 飞，等). Chin. Pharm. J.(中国药学杂志)，2005，40(19): 1500. [13] HE Hua，WANG Ling-li，LIU Xu-hui，et al(何 华，王羚郦，刘旭辉，等). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2006，26(8): 1516. [14] Rieutord A, Prognon P, Brion F, et al. Analyst，1997，122：59R.
