利用ATR-FTIR研究脂质纳米粒的鼻黏液渗透性

王健敏¹, 李雪梅¹, 马士超¹, 李志勇¹, 唐华东^2,^*, 马凤森^1,^*

Application of ATR-FTIR Spectroscopy to Evaluate the Permeability of Lipid Nanoparticles in Nasal Mucus

WANG Jian-min¹, LI Xue-mei¹, MA Shi-chao¹, LI Zhi-yong¹, TANG Hua-dong^2,^*, MA Feng-sen^1,^*

不同粒径PEG脂质体在黏液中不同时间点的ATR-FTIR图谱 (a): 69 nm PEG脂质体; (b): 124 nm PEG脂质体; (c): 183 nm PEG脂质体; (d): 249 nm PEG脂质体; (e): 303 nm PEG脂质体; (f): 419 nm PEG脂质体