| 光谱学与光谱分析 |
|
|
|
|
|
| Visible Light Reflectance Spectrum for Measurement of Cancerous Tissue |
| WANG Cheng1,FAN Jin2,REN Qiu-shi2 |
1. Institute of Biomedical Optics and Optometry Optics, University of Shanghai for Science and Technology, Shanghai 200093, China
2. Institute for Laser Medicine & Bio-photonics, Shanghai Jiaotong University, Shanghai 200240, China |
|
|
|
|
Abstract A goal the authors always pursue is to realize diagnosis of precancer in vivo, real-time and non-invasive. In the present paper, results of diagnosis of certain cancer were obtained by pathological analysis of several samples, and then the visible light reflectance spectrum property of cancerous tissue was acquired by the comparison with the reflectance spectrum of normal tissue in the same organ. It was found that the main result of change in the reflectance spectrum was caused by the increases in hemoglobin and deoxygenated hemoglobin. The cancerous tissue has a lower reflectance in visible spectrum and has the strongest change in the absorption at 630 nm. Absorption peaks in the reflectance spectrum indicated that there are abundant of oxygenated hemoglobin and deoxygenated hemoglobin in the cancerous tissue. It is the same characteristics as in the cancerous tissue. It was fully indicated experimentally that visible light reflectance spectrum can distinguish normal and cancerous tissue.
|
|
Received: 2006-08-08
Accepted: 2006-11-08
|
|
|
|
Corresponding Authors:
WANG Cheng
E-mail: shhwangcheng@yahoo.com.cn
|
|
[1] LUO Qing-ming, GONG Hui, LIU Xian-de, et al(骆清铭, 龚 辉, 刘贤德，等). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 1997, 17(3): 105.
[2] CHEN Wei, HE Bin, WEI Guang-hun, et al(陈 炜, 何 斌, 魏光辉, 等). Optical Technology(光学技术), 1998, 1: 70.
[3] Lilian de Oliveira Nunes, Airton A Martin, Landulto Silveira, et al. SPIE,2003, 4955: 546.
[4] Michael Jachson, Kwith Kim, John Tetteh, et al. SPIE, 1998, 3257: 24.
[5] LING Xiao-feng, XU Zhi, XU Yi-zhuang, et al(凌晓锋，徐 智，徐怡庄, 等). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2005，25(2)：198.
[6] FENG Shang-yuan, CHEN Rong, LI Yong-zeng, et al(冯尚源, 陈 荣, 李永增, 等). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2005，25(5)：712.
[7] Rong Zhang, Wim Verkruysse, Bernard Chio. Journal of Biomedical Optics,2005, 10(2): 024030-1.
[8] Inokuchi S, Nakai H, Manabe Y. Proceedings International Conference on Pattern Recognition, 1998，2(16)：1065.
[9] Yvette N Mirabal, Sung K Chang, Edward Neely Atkinson. Journal of Biomedical Optics,2002, 7(4): 587.
[10] Perelman L T, Backman V, Wallace M, et al. Phys. Rev. Lett., 1998, 80: 627.
[11] Shai Friedland, Roy Soetikno, David Benaron. Gastrointestinal Endoscopy Clinics of North America,2004, 14: 539.
[12] Friedland S, Benaron D, Parachikov I, et al. Gastrointestinal Endoscopy,2003, 57: 492.
[13] XUE Ling-ling, ZHANG Chun-ping, ZHANG Jian-dong, et al(薛玲玲, 张春平, 张建东, 等). Laser and Optics Progress(激光与光电子进展), 1999, (11): 36. |
| [1] |
ZHANG Nan-nan1, 3, CHEN Xi-ya1，CHANG Xin-fang1, XING Jian1, GUO Jia-bo1, CUI Shuang-long1*, LIU Yi-tong2*, LIU Zhi-jun1. Distributed Design of Optical System for Multi-Spectral Temperature
Pyrometer[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 230-233. |
| [2] |
ZHANG Ning-chao1, YE Xin1, LI Duo1, XIE Meng-qi1, WANG Peng1, LIU Fu-sheng2, CHAO Hong-xiao3*. Application of Combinatorial Optimization in Shock Temperature
Inversion[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3666-3673. |
| [3] |
HE Qing-yuan1, 2, REN Yi1, 2, LIU Jing-hua1, 2, LIU Li1, 2, YANG Hao1, 2, LI Zheng-peng1, 2, ZHAN Qiu-wen1, 2*. Study on Rapid Determination of Qualities of Alfalfa Hay Based on NIRS[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3753-3757. |
| [4] |
BAI Bing1, 2, 3, CHEN Guo-zhu2, 3, YANG Wen-bin2, 3, CHE Qing-feng2, 3, WANG Lin-sen2, 3, SUN Wei-min1*, CHEN Shuang1, 2, 3*. The Study on Precise and Quantitative Measurement of Flame OHConcentration by CRDS-CARS-PLIF Techniques[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3955-3962. |
| [5] |
LIU Wei1, 2, ZHANG Peng-yu1, 2, WU Na1, 2. The Spectroscopic Analysis of Corrosion Products on Gold-Painted Copper-Based Bodhisattva (Guanyin) in Half Lotus Position From National Museum of China[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3832-3839. |
| [6] |
SHEN Ying, WU Pan, HUANG Feng*, GUO Cui-xia. Identification of Species and Concentration Measurement of Microalgae Based on Hyperspectral Imaging[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3629-3636. |
| [7] |
LIU Wen-bo, LIU Jin, HAN Tong-shuai*, GE Qing, LIU Rong. Simulation of the Effect of Dermal Thickness on Non-Invasive Blood Glucose Measurement by Near-Infrared Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(09): 2699-2704. |
| [8] |
YAN Xue-jun1, ZHOU Yang2, HU Dan-jing1, YU Dan-yan1, YU Si-yi1, YAN Jun1*. Application of UV-VIS Diffuse Reflectance Spectrum, Raman and
Photoluminescence Spectrum Technology in Nondestructive
Testing of Yellow Pearl[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(06): 1703-1710. |
| [9] |
CHEN Xiao-li1, LI You-li1, LI Wei3, WANG Li-chun1, GUO Wen-zhong1, 2*. Effects of Red and Blue LED Lighting Modes on Spectral Characteristics and Coloring of Tomato Fruit[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(06): 1809-1814. |
| [10] |
XU Qi-lei, GUO Lu-yu, DU Kang, SHAN Bao-ming, ZHANG Fang-kun*. A Hybrid Shrinkage Strategy Based on Variable Stable Weighted for Solution Concentration Measurement in Crystallization Via ATR-FTIR Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(05): 1413-1418. |
| [11] |
LOU Deng-cheng, RAO Wei*, SONG Jun-ling, WANG Kai, JIANG Ya-jing, GUO Jian-yu. Research of Carbon Monoxide Concentration Measurement in Combustion Field by Off-Axis Integrated Cavity Output Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(12): 3678-3684. |
| [12] |
YAN Jun1, FANG Shi-bin1, YAN Xue-jun1, SHENG Jia-wei2, XU Jiang1, XU Chong3, ZHANG Jian2*. Study on the Common Effect of Heat Treatment, Dyeing or Irradiation Treatment on UV-Vis Diffuse Reflectance Spectra of Pearls[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(12): 3697-3702. |
| [13] |
FANG Shi-bin1, JIANG Yang-ming1, YAN Jun1, 2, YAN Xue-jun1, ZHOU Yang3, ZHANG Jian2*. The Types of UV-Vis Diffuse Reflectance Spectra of Common Gray Pearls and Their Coloring Mechanism[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(12): 3703-3708. |
| [14] |
LONG Jiang-xiong1, 2, ZHANG Yu-jun1*, SHAO Li1*, YE Qing1, 2, HE Ying3, YOU Kun3, SUN Xiao-quan1, 2. Traceable Measurement of Optical Path Length of Gas Cell Based on Tunable Diode Laser Absorption Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(11): 3461-3466. |
| [15] |
CHEN Cheng1, LI Xiao-ling1, WU Jin-jie2, CHEN Xiang-lei1, WU Rong-jun1, XU Xiao-hui1, ZHU Guo-hua1. MC Simulation and Energy Spectrum Measurement of K Fluorescence Radiation Field[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(11): 3595-3600. |
|
|
|
|
