光谱学与光谱分析 |
|
|
|
|
|
Nodular Goiter Surface Detection by FTIR Spectroscopy |
LING Xiao-feng1, XU Zhi1, XU Yi-zhuang2*, ZHOU Su1, ZHANG Neng-wei3, WANG Li-xin1, HOU Chun-sheng1, ZHANG Yuan-fu2, ZHOU Xiao-si1, WU Jin-guang2 |
1. Department of General Surgery, Third Hospital of Peking University, Beijing 100083, China 2. College of Chemistry, Peking University, Beijing 100871, China 3. Department of General Surgery, Beijing Shijitan Hospital, Beijing 100038, China |
|
|
Abstract A novel non-invasive diagnosis method of nodular goiter is proposed in the present study by recording FTIR spectra on the skin overlying thyroids using fiber optical technique and attenuated total reflection probe. FTIR spectra from 20 nodular goiters and 34 normal controls were collected. Twenty seven spectral variables of 13 bands including peak position and relative intensities were extracted from the FTIR spectra so that statistic work could be conducted using SPSS. The results demonstrate that peak positions of 2 925 and 1 250 cm-1 both shifted toward lower wave number(P<0.05) in the FTIR spectra of nodular goiter. The relative intensity ratios of H1 740/H1 460, H1 160/H1 460, and H1 160/H1 120 decreased significantly in FTIR spectra of nodular goiter (P<0.05). Inversely, H1 080/H1 460 increased significantly (P<0.05) in nodular goiter. The above statistic differences suggest that nodular goiter may produce some characteristic chemical substance which can diffuse onto the surface of skin and therefore be detectable using FTIR spectroscopy with fiber optic techniques. These differences are the basis of diagnosing nodular goiter by FTIR surface detection.
|
Received: 2005-04-01
Accepted: 2005-06-08
|
|
Corresponding Authors:
XU Yi-zhuang
|
|
Cite this article: |
LING Xiao-feng,XU Zhi,XU Yi-zhuang, et al. Nodular Goiter Surface Detection by FTIR Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2005, 25(12): 1955-1958.
|
|
|
|
URL: |
https://www.gpxygpfx.com/EN/Y2005/V25/I12/1955 |
[1] WANG Jian-sheng, XU Yi-zhuang, SHI Jing-sen,et al(王健生, 徐怡庄, 石景森,等). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2003, 23(15) : 863. [2] LI Qing-bo, YANG Li-min, LING Xiao-feng,et al(李庆波, 杨丽敏, 凌晓锋, 等). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2004, 24(4): 414. [3] LING Xiao-feng, XU Zhi, XU Yi-zhuang, et al(凌晓锋, 徐 智, 徐怡庄,等). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2005, 25(2): 198. [4] LI Qing-bo,XU Zhi,XU Yi-zhuang, et al(李庆波, 徐 智, 徐怡庄, 等). Chemical Journal of Chinese Universities(高等学校化学学报),2004, 25(11): 2010. [5] ZHAN Shao-kang, JIN Pi-huan (詹少康, 金丕焕). Statistic Test for Means of Two Groups. 39. In JIN Pi-huan (Editor)(金丕焕主编). Statistic Methods for Medicine(医用统计方法). Shanghai: Shanghai Medical University Press(上海:上海医科大学出版社),1992. [6] XU Yi-zhuang, ZHANG Yuan-fu, YANG Li-min, et al(徐怡庄, 张元福, 杨丽敏, 等). Chemical Journal of Chinese Universities(高等学校化学学报), 2004, 25(2): 348. [7] WU Jin-guang(Editor)(吴瑾光主编). The Techniques and Application of Modern Fourier Transform Infrared Spectroscopy(近代傅里叶变换红外光谱技术及应用). Beijing: Literature Press of Science and Technology(北京: 科学技术文献出版社), 1994.
|
[1] |
XU Qi-lei, GUO Lu-yu, DU Kang, SHAN Bao-ming, ZHANG Fang-kun*. A Hybrid Shrinkage Strategy Based on Variable Stable Weighted for Solution Concentration Measurement in Crystallization Via ATR-FTIR Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(05): 1413-1418. |
[2] |
WANG Zhuo1, 2, SU Bo-min1, 2*, YU Zong-ren1, 2, SHUI Bi-wen1, 2, ZHAO Jin-li1, 2, CUI Qiang1, 2, SHAN Zhong-wei1, 2, LI Qian3. In-Situ Non-Invasive FTIR Analysis of Conservation Materials on the Surface of Mural Paintings in Prince Shi’s Palace of the Taiping Heavenly Kingdom[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2020, 40(02): 356-361. |
[3] |
LI Jing1, TIAN Hong-xiang1*, SUN Yun-ling1, MING Ting-feng1, SHENG Chen-xing2, 3. Application of FTIR Spectrum in Quantitatively Monitoring Oil Contaminants[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2019, 39(11): 3459-3464. |
[4] |
YE Song1,ZHANG Bing-ke1, 2,YANG Hui-hua1,ZHANG Wen-tao1,DONG Da-ming2*. Identification of Beef Spoilage Processes Using the Infrared Spectrum of Volatiles[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2017, 37(09): 2751-2755. |
[5] |
LIU Na, WEI Xiu-li*, GAO Min-guang, XU Liang . A Quantitative Analysis Method of Water-Soluble Inorganic Ions with ATR-FTIR Spectroscopy [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2015, 35(12): 3364-3368. |
[6] |
JIANG Ling1, LI Miao1, LI Chun1, SUN Hai-jun2, XU Li2, LIU Yun-fei* . Terahertz Spectroscopy of Biotin and Pyridoxine [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2015, 35(10): 2946-2951. |
[7] |
REN Li-bing, YANG Hong-lei, WEI Hao-yun, LI Yan . The Realization of Moving Mirror Scanning in FTIR Spectrometer Using Completely Digital Control Method [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2013, 33(08): 2263-2266. |
[8] |
GUO Cai-xia, YUE Tian-li*, YUAN Ya-hong, WANG Zhou-li, WANG Ling, CAI Rui . Study on Mechanism of Inactivated Cider Yeast Adsorbing Patulin by Fourier Transform Infrared Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2013, 33(03): 672-676. |
[9] |
LI Zhong-bing, XU Xian-ze*, LE Yi, XU Feng-qiu, LI Jun-wei. Motion Control of Moving Mirror Based on Fixed-Mirror Adjustment in FTIR Spectrometer[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2012, 32(08): 2295-2298. |
[10] |
SUN Qi-gang1, LIU Ya-qi1,XU Yi-zhuang2,ZHANG Yuan-fu2,WU Jin-guang2,ZHOU Xiao-si1, XU Zhi1, LING Xiao-feng1* . Fourier Transform Infrared Sqectroscopic Study on Gallbladder Carcinoma [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2010, 30(12): 3195-3198. |
[11] |
CHU Yan-hong1, 2, WANG Jing-wu1*, ZHANG Guo-bao2, ZHAO Gen-suo2, YU Shou-zhi2, REN Zhi-yong2. Study on the Solid State Transformation of PET/Nano-CaCO3 Composites by Variable Temperature FTIR Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2010, 30(02): 336-339. |
[12] |
LIU Ya-qi1,GAO Mei-juan1,3,XU Yi-zhuang2,SUN Qi-gang1,ZHANG Xiao-qing1,XU Zhi1,ZHANG Yuan-fu2, WU Jin-guang2,ZHOU Xiao-si1,LING Xiao-feng1*. Investigation on Fourier Transform Infrared Spectrum of Metastatic Lymph Node in Thyroid Cancer [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2009, 29(11): 2917-2921. |
[13] |
CHU Yan-hong1,2,ZHANG Guo-bao2,ZHAO Gen-suo2,YU Shou-zhi2,WANG Jing-wu1*,LI Bin-jie3 . Study on the Reaction Mechanism of Surface Modified Nano-CaCO3 Particles Using w-Undecenoic Acids as Modifier by FTIR Difference Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(08): 1510-1513. |
[14] |
DING Shi-lei, ZHANG Gang-sheng* . FTIR Spectroscopic Study on Natural Aragonitic Ceramics-Bivalve Shells of Hyriopsis Cumingii [J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(12): 2200-2202. |
[15] |
ZHAO Liang1, Gayle Newcombe2, Leanne Britcher3. The Characteristic IR Spectra of Microcystin-LR[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(06): 1051-1053. |
|
|
|
|