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Study on the Effect of He-N2 Ratio in Mixed Carrier Gas on Separation of VOC Aliasing Peaks in FAIMS |
SHI Hai-xia1, XU Qing1, 2, WANG Han2, 3, LIU You-jiang2, LI Shan2, HU Jun2, 3, LI Yue1, 2*, CHEN Chi-lai2* |
1. College of Automotive and Transportation Engineering, Hefei University of Technology, Hefei 230009, China
2. State Key Laboratory of Sensing Technology, Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, China
3. Department of Automation, University of Science and Technology of China, Hefei 230027, China |
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Abstract Carrier gas mixing as one of the most important methods to improve the separation ability of high Field Asymmetric waveform Ion Mobility Spectrometry (FAIMS) has been widely used in the field of bio macromolecule mass spectrometry, while there is a lack of some research in environmental small molecules. In this paper, five typical volatile organic compounds (VOCs), including o-xylene, isobutanol, n-hexane, acetic acid and acetone, were chosen to study the effect of N2-He mixing ratio on the peak position, resolution and ion pass rate of monomers and dimer ion. The results showed that with the increase of the proportion of He in the carrier gas of FAIMS, the peak position of the monomer and dimer ion in five VOCs shifts, and the peak of the monomer and the dimer were different, and the monomer peak shift increased first and then decreased, while the dimer peak position shift increased gradually. With the increase of the percentage of He, the resolution of FAIMS for aliasing peaks of five VOCs gradually increased and tended to saturate at last, where the saturated helium ratio was: 20%, 30%, 10%, 40% and 20%, respectively. In addition, with the increase of the percentage of helium, the signal intensity of o-xylene, isobutanol, n-hexane and acetone had no obvious change, while that of acetic acid decreased significantly. This study provided a feasible method for improving the separation ability of FAIMS and validating the effectiveness of Blanc’s law under high electric field applied in the field of small molecules.
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Received: 2018-08-17
Accepted: 2019-01-10
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Corresponding Authors:
LI Yue, CHEN Chi-lai
E-mail: 344584314@qq.com;chlchen@iim.ac.cn
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[1] Kanu A B, DwivediP, Tam M, et al. Journal of Mass Spectrometry, 2008, 43(1): 1.
[2] Prasad S, Belford M W, Dunyach J J, et al. Journal of the American Society for Mass Spectrometry, 2014, 25(12): 2143.
[3] ZHAO Cong, CHEN Chi-lai, CHEN Ran, et al(赵 聪,陈池来,陈 然,等). Analytical Instrumentation(分析仪器), 2012,(2): 6.
[4] WU Zhi-yuan, YU Jian-wen, LIU You-jiang, et al(吴志远,余健文,刘友江,等). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2017, 37(10): 3170.
[5] Bailly C L, Cormant F, Garcia P, et al. Analyst, 2012, 137(10): 2445.
[6] Leonard C, Rorrer L C, Yost R A. International Journal of Mass Spectrometry, 2011, 300(2-3): 173.
[7] Prieto M, Tsai C W, Boumsellek S, et al. Analytical Chemistry, 2011, 83(24): 9237.
[8] ZHANG Jie, LI Ling-feng, GUO Da-peng, et al(张 洁,李灵峰,郭大鹏,等). Chinese Journal of Analytical Chemistry(分析化学), 2013, 41(7): 986.
[9] Schrader W, Xuan Y, Gaspar A. European Journal of Mass Spectrometry, 2014, 20(1): 43.
[10] Ells B, Barnett D A, Purves R W, et al. Journal of Environmental Monitoring, 2000, 2(5): 393.
[11] Mccooeye M A, Ells B, Barnett D A, et al. Journal of Analytical Toxicology, 2001, 25(2): 81.
[12] Shvartsburg A A, Danielson W F, Smith R D. Analytical Chemistry, 2010, 82(6): 2456.
[13] Santiago B G, Harris R A, Isenberg S L, et al. J. Am. Soc. Mass Spectrom., 2015, 26(10): 1746.
[14] Shvartsburg A A, Tang K, Smith R D. Analytical Chemistry, 2004, 76(24): 7366.
[15] LIN Bing-tao, CHEN Chi-lai, KONG De-yi, et al(林丙涛,陈池来, 孔德义,等). Chinese J. Anal. Chem.(分析化学), 2010, 38(7): 1027.
[16] Krylova N, Krylov E, Eiceman G A, et al. Journal of Physical Chemistry A, 2003, 107(19): 3648. |
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