Surface-Enhanced Raman Spectra of Natural Tissue and Cancerous Tissue of Lung
LIU Yan-nan1,3,ZOU Zu-quan2,3,LIU Yan-qing4,XU Xiao-xuan1,3,YU Gang1,3,ZHANG Cun-zhou1,3
1. Photonics Center of School of Physics, Nankai University, Tianjin 300071, China 2. Department of Biophysics, School of Physics, Nankai University, Tianjin 300071, China 3. The Key Laboratory of Advanced Technique and Fabrication for Weak-Light Nonlinear Photonics Materials, Ministry of Education, Nankai University, Tianjin 300457, China 4. Pathology Staff Room of Medical College Chinese People’s Armed Police Force, Tianjin 300162,China
Abstract：Surface-enhanced Raman spectra of natural tissue and cancerous tissue of lung from 300 to 1 700 cm-1 were measured. In the cancerous tissue of lung, the orderly conformations of amidesⅢ and amidesⅠof the main chains in protein such as α-helix，β-corner and no rules curly were damaged seriously; conversely, the extendable vibration of skeleton C—N and skeleton C—C increased. Side chains change became complicated. In general, the content of nucleic acids increases in the cancer tissue of lung. The lengthways conformations of lecithoid chains is out-of-order in the cancerous tissue of lung compared with the natural ones.
Key words：Surface-enhanced Raman spectra;Natural tissue of lung;Cancerous tissue of lung
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