Abstract:The present paper puts forward multi-wavelength pulse oxygen saturation measurement based on dynamic spectroscopy to do the non-invasive determination of oxygen saturation. Compared to conventional ways, the new method makes full use of more wavelengths light and improves the measurement accuracy. During the experiment, the in-vivo measurements were carried out on 60 patients and their spectroscopic data were collected by the high sensitivity type fiber optic spectrometer. Single-trial estimation method was used to extract the dynamic spectroscopy at the wavelengths of 606.44~987.55 nm. Oxygen saturation obtained from arterial blood gas analysis is regarded as the true value. Synergy interval partial least square (siPLS) was used to establish the calibration model of subjects’ oxygen saturation values against dynamic spectroscopy data. The relative error of prediction is ±0.017 6, but the relative error of the subjects in the same set measured by the patient monitor which was two-wavelength measure system is ±0.116 4. Measurement results show that the use of the high sensitivity type fiber optic spectrometer to collect multi-wavelength spectroscopic data and dynamic spectroscopy method to process data can do better in improving the accuracy of the oxygen saturation measurement.
Key words:Oxygen saturation;Dynamic spectroscopy;Multi-wavelength;Single-trial estimation method;Synergy interval partial least square
[1] LIU Guang-da, GUO Wei, ZHU Ping, et al(刘光达,郭 维,朱 平,等). Laser & Infrared(激光与红外), 2009, 39(2): 169. [2] Rosychuk R J, Hudson-Mason A, Eklund D, et al. Journal of Neonatology, 2011, 101(1): 14. [3] Ynt G, Korhan E, Khorshid L. Journal of Applied Nursing Research, 2011, 24(4): 39. [4] LI Gang, LI Shang-ying, LIN Ling, et al(李 刚,李尚颖,林 凌,等). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2006,26(10):1821. [5] ZHOU Hong-jian, CAI Gui-yan(周洪建,蔡桂艳). Chinese Journal of Biomedical Engineering(中国生物医学工程学报), 2007, 26(5): 680. [6] SONG Jun-jie, WANG Zhe, JIN Hai-long, et al(宋俊杰,王 哲,金海龙,等). Laser & Infrared(激光与红外), 2010, 40(1): 62. [7] Burns P, Driessen B, Boston R, et al. Veterinary Anaesthesia & Analgesia, 2006, 33(5): 281. [8] Schoevers J, Scheffer C, Dippenaar R. IEEE Transactions on Biomedical Engineering, 2009, 56(3): 846. [9] JIA Ping, ZHANG Bao-ju, ZHANG Zhi-yong, et al(贾 萍,张宝菊,张志勇,等). Journal of Infrared and Millimeter Waves(红外与毫米波学报), 2010, 29(2): 132. [10] LI Gang, MEN Jian-long, SUN Zhao-min, et al(李 刚,门剑龙,孙兆敏,等). Journal of Tianjin University(天津大学学报),2011,16(1):186. [11] LIN Fen-fang, CHEN Zhu-lu, WANG Ke, et al(林芬芳,陈祝炉,王 珂,等). Journal of Infrared and Millimeter Wave(红外与毫米波学报), 2009, 28(4): 277.