Determination of Trace Elements in Mongolian Medicine Zidianling Curing Allergic Purpura Disease by ICP-AES
E Er-deng-sang1,HANG Gai-ba-te-re2,BA Tu1
1. Chemistry & Environment Science College, Inner Mongolia Normal University, Huhhot 010022, China 2. The Chinese and Mongolian Hospital of Inner Mongolia, Huhhot 010022, China
Abstract：During the study of the Mongolian medicine Zidianling, the authors found that the Mongolian medicine Zidianling contains great amount of trace elements in which human-body-needed trace elements are fairly much but the heavy metals are very little. A method using ICP-AES with microwave digestion was studied for the determination of 15 elements including Ca, Mg, Sr, Fe, Mn, Zn, Cu, Pb, etc. in Mongolian medicine-Zidianling. The major function of this medicine is clearing away heat and removing toxic substances, and cooling blood to stop bleeding. To explain the Zidianling’s clinical effects, the authors chose 260 allergic purpura patients with 140 male and 120 female. The youngest was 6 years old, the oldest was 62 years old. Most of patients were between 6 and 16, accounting for nearly 90%. The results of clinical effects show that 234 patients were cured, roughly 90% of the total number Thirteen patients showed obvious effects (5% of the total number) and 11 had effective cures of illnesses (4.23% of the total number). Two patients had no cures of illnesses (0.77% of the total number). And the integrated effective rate may reach 99.23%. The results show that Mongolian medicine Zidianling has great amount of trace elements and its Sr content is different from other Mongolian medicines and is especially high. The recoveries of standard addition are in the range of 94.63%-106.40%. The relative standard deviation RSD≤3.17%, and the detection limit is in the range of ≤0.009 μg·mL-1.
Key words：Mongolian medicine zidianling;Trace elements;Allergic purpura;ICP-AES
额尔登桑1,杭盖巴特尔2,巴图1. ICP-AES法测定蒙药紫癜灵中多种微量元素[J]. 光谱学与光谱分析, 2008, 28(11): 2679-2683.
E Er-deng-sang1,HANG Gai-ba-te-re2,BA Tu1. Determination of Trace Elements in Mongolian Medicine Zidianling Curing Allergic Purpura Disease by ICP-AES. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2008, 28(11): 2679-2683.
[1] ZHANG Yuan, ZHU Er-yi, ZHUANG Shi-xia, et al(章 元，朱尔一，庄峙厦，等). Chem. J. Chinese Universities(高等学校化学学报), 1998, 19(7): 1054. [2] YAN Xiu-ping, NI Zhe-ming(严秀平，倪哲明). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2001, 21(2): 129. [3] SUN Han-wen, LI Ai-hong, SUN Jian-min(孙汉文， 李爱红，孙建民). Journal of Hebei University(Natural Science Edition)(河北大学学报·自然科学版)，2002, 22(4): 400. [4] ZHANG Qi-feng, LIU Qin, YAO Xing(张奇凤，刘 琴，姚 兴). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2004, 24(3): 366. [5] CHEN Jun, YAO Cheng, OUYANG Ping-kai(陈 军，姚 成，欧阳平凯). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2005, 25(4): 560. [6] LI Hai-long, WANG Li-zhen, WANG Wu-yi(李海龙，王丽珍，王五一). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2005, 25(8): 1344. [7] ZHANG Jun, YUAN Zhuo-bin(张 君，袁倬斌). Chinese Journal of Analysis Laboratory(分析试验室)，2005，24(11)：80. [8] HANG Gai-ba-te-er(杭盖巴特尔). Journal of Medicine & Pharmacy of Chinese Minoriti(中国民族医药杂志)，2003, 10(4): 5. [9] YI Xin-ping，LIU Jian-ping，LI Ge(易新萍，刘建平，李 革). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2004, 24(7): 890. [10] Boss Charles B, Fredeen Kenneth J. Concept Instrmentation and Techniques in Inductively Coupled Plasma Optical Emission Spectrometry. Norwalk, Perkin-Elmer Corporation, 1999. 1. [11] FAN Xue-seng，ZHANG Ying-xin，WANG Cai-lan, et al(范学森，张迎新，王彩兰, 等). Studies of Trace Elements and Health(微量元素与健康研究)，1999, 16(1): 51. [12] E Er-deng-sang, BAO Yin-da-lai, NA Ren-ge-ri-le(额尔登桑，宝音达赖，娜仁格日乐). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2006，26 (11)：2134. [13] FU Chuan, QI Jun-sheng(付 川，祁俊生). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2003, 23(3): 617. [14] E Er-deng-sang, BAO Yin-da-lai, HANG Gai-ba-te-er(额尔登桑，宝音达赖，杭盖巴特尔). Chinese Traditional Patent Medicine(中成药)， 2007，29(5)：704. [15] WU Yong-jun, LIU Jie, WU Yu-ming, et al(吴拥军，刘 洁，吴予明，等). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2005, 25(12): 2076. [16] WANG Jian-ke, REN Yong-quan, CHEN Hui-ling, et al(王建科，任永全，陈惠玲，等). Studies of Trace Elements and Health(微量元素与健康研究)，2003，20(6)：28. [17] WANG Yi(王 奕). Studies of Trace Elements and Health(微量元素与健康研究)，2003，20(4)：23. [18] YAN Shi-ming, LI Zeng-xi, XIONG Li-ping(颜世铭，李增禧，熊丽萍). Guang dong Trace Elements Science(广东微量元素科学), 2002，9(10)：1. [19] ZHANG Li-juan, GU Xue-xin, ZHOU Yong-yi(张丽娟，谷学新，周勇义). Journal of Capital Normal University(Natural Science Edition)(首都师范大学学报·自然科学版)，2004, 25(1): 34.
