Abstract:Terahertz science and technology is increasingly emphasized in science and industry,and has progressed significantly in recent years.There is an important aspect of attention in the application of terahertz technology to medicine.The overview of the terahertz characters, terahertz spectroscopy and terahertz imaging technology is introduced.This paper focuses on reviewing the use of and research progress in terahertz spectroscopy and terahertz imaging technology in medical testing and diagnosis.Furthermore,the problems to be solved and development directions of terahertz spectroscopy and terahertz imaging technology are discussed.
[1] Ronne C,Keiding S R. Journal of Molecular Liquids,2002,101(1-3):199. [2] Berry E,Walker G C,Fitzgerald A J,et al. Journal of Laser Applications,2003,15(3):192. [3] Hu B B,Nuss M C. Optics Letters,1995,20(16):1716. [4] Taday P F,Bradley I V,Arnone D D. Journal of Biological Physics,2003,29(2-3):109. [5] Rungsawang R,Ueno Y,Tomita I,et al. The Journal of Physical Chemistry B,2006,110(42):21259. [6] Kikuchi N,Tanno T,Watanabe M,et al. Analytical Sciences,2009,25(3):457. [7] Kutteruf M R,Brown C M,Iwaki L K,et al. Chemical Physics Letters,2003,375(3-4):337. [8] Yamamoto K,Tominaga K,Sasakawa H,et al. Biophysical Journal,2005,89(3):L22. [9] Yoshida H,Ogawa Y,Kawai Y,et al. Applied Physics Letters,2007,91(25):253901. [10] Ogawa Y,Hayashi S,Oikawa M,et al. Optics Express,2008,16(26):22083. [11] Png G M,Falconer R J,Fischer B M,et al. Optics Express,2009,17(15):13102. [12] Liu R,He M,Su R,et al. Biochemical and Biophysical Research Communications,2010,391(1):862. [13] Wittlin A,Genzel L,Kremer F,et al. Physical Review A,1986,34(1):493. [14] Brucherseifer M,Nagel M,Haring Bolivar P,et al. Applied Physics Letters,2000,77(24):4049. [15] Fischer B M,Walther M,Uhd Jepsen P. Physics in Medicine and Biology,2002,47(21):3807. [16] Alexandrov B S,Gelev V,Bishop A R,et al. Physics Letters A,2010,374(10):1214. [17] Arora A,Luong T Q,Krüger M,et al. Analyst,2012,137(3):575. [18] Singh R S,Tewari P,Bourges J L,et al. Terahertz Sensing of Corneal Hydration. in:32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society,Buenos Aires,Aug. 31-Sept. 4,2010. [19] Bennett D B,Taylor Z D,Tewari P,et al. Journal of Biomedical Optics,2011,16(5):57003. [20] Bennett D B,Taylor Z D,Tewari P,et al. Journal of Biomedical Optics,2012,17(9):97008. [21] Png G M,Flook R,Ng B W,et al. Electronics Letters,2009,45(7):343. [22] Bakopoulos P,Karanasiou I,Pleros N,et al. Measurement Science and Technology,2009,20(10):104001. [23] Sim Y C,Maeng I,Son J. Current Applied Physics,2009,9(5):946. [24] Schirmer M,Fujio M,Minami M,et al. Biomedical Optics Express,2010,1(2):354. [25] Hirmer M,Danilov S N,Giglberger S,et al. Journal of Infrared, Millimeter, and Terahertz Waves,2012,33(3):366. [26] Stringer M R,Lund D N,Foulds A P,et al. Physics in Medicine and Biology,2005,50(14):3211. [27] Kan W C,Lee W S,Cheung W H,et al. Biomedical Optics Express,2010,1(3):967. [28] Jung E,Choi H J,Lim M,et al. Biomedical Optics Express,2012,3(5):1110. [29] Bouclier M,Cavey D,Kail N,et al. Pharmacological Reviews,1990,42(2):127. [30] Taylor Z D,Singh R S,Culjat M O,et al. Optics Letters,2008,33(11):1258. [31] Wallace V P,Fitzgerald A J,Shankar S,et al. British Journal of Dermatology,2004,151(2):424. [32] Wallace V P,Fitzgerald A J,Pickwell E,et al. Applied Spectroscopy,2006,60(10):1127. [33] Joseph C S,Yaroslavsky A N,Neel V A,et al. Lasers in Surgery and Medicine,2011,43(6):457. [34] Jung E,Lim M,Moon K,et al. Journal of the Optical Society of Korea,2011,15(2):155. [35] Ashworth P C,Pickwell-MacPherson E,Provenzano E,et al. Virtual Journal for Biomedical Optics,2009,17(15):12444. [36] Wahaia F,Valusis G,Bernardo L M,et al.Journal of Molecular Structure,2011,1006(1-3):77. [37] Brun M,Formanek F,Yasuda A,et al. Physics in Medicine and Biology,2010,55(16):4615. [38] Sy S,Huang S,Wang Y X,et al. Physics in Medicine and Biology,2010,55(24):7587. [39] Zhang C H,Zhao G F,Jin B B,et al. Terahertz Science and Technology,2012,5(3):114. [40] Pickwell E,Cole B E,Fitzgerald A J,et al. Applied Physics Letters,2004,84(12):2190. [41] Pickwell E,Fitzgerald A J,Cole B E,et al. Journal of Biomedical Optics,2005,10(6):64021. [42] Png G M,Choi J W,Ng B W,et al. Physics in Medicine and Biology,2008,53(13):3501. [43] Sun Y,Fischer B M,Pickwell-MacPherson E. Journal of Biomedical Optics,2009,14(6):64017. [44] Oh S J,Kang J,Maeng I,et al.Optics Express,2009,17(5):3469. [45] Lee J,Yang J,Ko H,et al. Advanced Functional Materials,2008,18(2):258. [46] Huang X,EI-Sayed I H,Qian W,et al. Journal of the American Chemical Society,2006,128(6):2115. [47] Ronne C,Thrane L,Astrand P,et al. Journal of Chemical Physics,1997,107(14):5319. [48] Ferguson B,Abbott D. Microelectronics Journal,2001,32(12):943. [49] Handley J W,Fitzgerald A J,Berry E,et al. Physics in Medicine and Biology,2002,47(21):3885. [50] Yin X,Ng B W,Fischer B M,et al.IEEE Sensors Journal,2007,7(12):1597.