Equalization of Whole-Band Signal’s SNR in the Blood Components Noninvasive Measurement
LI Gang1, WANG Hui-quan1, ZHANG Hao1, LIN Ling1, WU Xiao-rong2, ZHANG Bao-ju2*
1. State Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin 300072, China 2. College of Physics and Electronic Information, Tianjin Normal University, Tianjin 300387, China
Abstract:To fully extend the category of blood components that can be noninvasively measured by dynamic spectrum (DS) method and to increase its measuring precision, an overall consideration of light source, tissue absorption and sensor’s sensitivity was made. Compensating the light source and adding the telecentric lens not only expand the spectral effective detecting range, but also balance the signal-to-noise ratio (SNR) of the photoelectric pulse in the whole band equalization. The integral SNR of DS signal was increased and the measurement bandwidth was expanded. The effectiveness of this method was validated by the quality evaluation criterion of DS data: the effective detecting range of visible DS was widened from 600~1 000 nm to 500~1 135 nm; the effective detecting range of near-infrared DS was widened from 900~1 100 nm to 900~1 700 nm. The results show that the design can create the condition for detection of new blood components noninvasively, and enhance the prediction accuracy of the blood components, for which noninvasive measuring using DS method has been achieved.
[1] Matthew E E, Hamid D. Opt Express, 2008, 16: 17780. [2] Jobsis F F. Science, 1977, 198: 1264. [3] LI Gang, LIU Yu-liang, LIN Ling, et al. 3rd International Symposium on Instrumentation Science and Technology, Xi’an, 2004. 875. [4] CHEN Xing-dan(陈星旦). Optics and Precision Engineering(光学精密工程), 2008, 16(5): 759. [5] Yamakoshi K, Yamakoshi Y. Journal of Biomedical Optics, 2006, 11(5): 1. [6] McMurdy J, Jay G, Suner S, et al. J. Biophoton., 2009, 2(5): 277. [7] Total Hemoglobin Measurements: Accuracy of Laboratory Devices and Impact of Physiologic Variation. http://www.masimo.it/hemoglobin/index.htm, 2009. [8] LAN Xiu-feng, LIU Ying,ZHU Tuo, et al(兰秀凤, 刘 莹, 朱 拓). Acta Photonica Sinca(光子学报), 2008, 37(3): 547. [9] XIAO Jun, WANG Long, LUO Qing-ming, et al(肖 君, 王 龙, 骆清铭, 等). Journal of Optoelectronics·Laser(光电子·激光), 2007, 18(9): 1135. [10] Wang Huiquan, LI Gang, ZHAO Zhe, et al. Life System Modeling and Intelligent Computing Lecture Notes in Computer Science, 2010, 6630: 67. [11] QE65000 Data Sheet.http://www.oceanopticschina.cn/Products/qe65000.asp, 2010.