Spectrometric Determination of Trace Elements in Anticancer New Medicine Fagopyrum Dibotrys
WANG Ji-yong1，WANG Yuan-zhong2，ZENG Yan1，LI Jin-tong1
1. Yunnan Traditional & Herbal Co., Ltd.，Kunming 650041, China 2. Institute of Medicinal Plant, Yunnan Academy of Agricultural Sciences, Kunming 650223, China
Abstract：The golden buckwheat Fagopyrum dibotrys produced in Yunnan has a unique anti-cancer effects.It is a main raw material of “Wei Mai ning” capsules which is the national second-class anti-cancer drug. The present paper used(5∶1) mixed acid as digestive juice to process the sample, and determine the twelve elements including K, Ca, Cu, Na, Mg, Mn, Fe, Zn, Pb, Cr, Cd and Co in the Fagopyrum dibotrys by inductively coupled plasma atomic emission spectrometry(ICP-AES). The detection limits of this method were 0.017～0.084 μg·mL-1, the RSDs (n=8) were all 0.09%～1.87%, and the addition standard recoveries(ASR)(n=8) were 98.2%～107.4% for all elements. The research results showed that there is rich K(1 477.3 μg·g-1) in the Fagopyrum dibotrys, there are not harmful elements Cd and Pb, and this result is mainly related to the geochemistry background where the sample lived. The contents of seven remaining kinds of elements ranked as Na(826.1)>Ca(765.2>Mg(493.4)>Zn(112.7)>Fe(56.5)>Cu(11.4)>Mn(4.49 μg·g-1). This result provides some theoretical basis for the study of internal relations between trace elements in Fagopyrum dibotrys and efficacy. It’ s also useful for better development and utilization of the resource.
Key words：ICP-AES;Anticancer new medicine;Fagopyrum dibotrys;Trice elements
王继永1，王元忠2，曾 燕1，李进瞳1 . 抗癌新药金荞麦中微量元素的光谱测定[J]. 光谱学与光谱分析, 2011, 31(01): 253-255.
WANG Ji-yong1，WANG Yuan-zhong2，ZENG Yan1，LI Jin-tong1 . Spectrometric Determination of Trace Elements in Anticancer New Medicine Fagopyrum Dibotrys . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2011, 31(01): 253-255.
[1] LIN Hong-sheng(林洪生). Journal of Chinese Integrative Medicine(中西医结合学报)，2004，2(1)： 72. [2] XIONG Liu-bo, YANG Zheng, XU Yan, et al(熊六波，杨 拯，徐 艳，等). Journal of Liaoning Universtity of Traditional Chinese Medicine(辽宁中医药大学学报)，2008，10(9)： 132. [3] LIU Hong-gao, WANG Yuan-zhong(刘鸿高，王元忠). Spectroscopy and Spectral Analysis(光谱学与光谱分析)，2010，30(1)： 259.
