Determination of Trace Copper and Zinc in Hypertension Complicated with Hyperlipemia by Atomic Absorption Spectrophotometry
HE Bang-ping1, LI Dong-fang2, MA Jian-wei3, CHEN Jie1, LIU Xiao-yu1, ZHANG Xin-rong1, XU Jian-ming1
1. College of Pharmacy, Second Military Medical University, Shanghai 200433, China 2. College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, China 3. Hospital of Shanghai Pudong Xinqu Dongfang, Shanghai 200120, China
Abstract：The serum levels of Zn, Cu, cholesterol (Ch) and triglyceride (TG) were determined in 44 patients with hypertension complicated with hyperlipemia, 42 patients with hypertension(HP) and 30 healthy controls by atomic absorption spectrophotometry and automatic biochemical analytical instrument of reagent kit. It was found that the contents of Zn, Ch, TG and Zn/Cu ratio in hypertension complicated with hyperlipemia were significantly higher than in HP and control, while Cu in hypertension complicated with hyperlipemia was significantly lower than in HP and control. The contents of Zn, Ch, TG and Zn/Cu ratio in hypertension were significantly increased. It is suggested that hypertension complicated with hyperlipemia is closely related with Zn and Cu.
Key words：Atomic absorption spectrophotometry;Hypertension complicated with hyperlipemia;Serum;Copper;Zinc
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