Infrared Spectrum Analysis of Admixture Decoction of Herba Ephedrae with Ramulus Cinnarnomi
LIN Wen-shuo1,2, GUO Shao-zhong2, HUANG Hao3, CHEN Rong1*, FENG Shang-yuan1, LI Yong-zeng1, CHEN Wei-wei1
1. Key Laboratory of Optoelectronic Science and Technology for Medicine, Ministry of Education, Fujian Normal University,Fuzhou 350007, China 2. Department of Mathematics and Physics,Fujian University of Technology, Fuzhou 350108, China 3. Department of Public Management, Fujian University of Traditional Chinese Medicine, Fuhzou 350108, China
Abstract:The infrared spectra of decoction of herba ephedra and ramulus cinnarnomi and the mixed decoction of herba ephedra + ramulus cinnarnomi were tested. The change in the mixed decoction was discussed to study the relationship between herba ephedra and ramulus cinnarnomi after decoction. The results showed that some components of herba ephedra and ramulus cinnarnomi were retained in the mixed decoction of herba ephedra+ramulus cinnarnomi, such as 1 205 and 1 074 cm-1, but some components that never appeared in the two component spectra increased, such as 1 394 and 678 cm-1. New absorption peaks were generated in the mixed decoction of herba ephedra + ramulus cinnarnomi,such as 757 and 407 cm-1. It can be showed that there are differences in the chemistry environment of the various chemical groups in the three decoctions introduced above, and with the variation in absorption peak position, possibly some new chemical compositions were created. Medical ingredients in the decoction are not simply the addition of herba ephedra and ramulus cinnarnomi.based on the studies of infrared spectrum of the mixed decoction of herba ephedra + ramulus cinnarnomi, and the new notion of prescription spectroscopy was proposed.
Key words:Recipe’s spectroscopy;Infrared spectroscopy;Herba ephedra;Ramulus cinnarnomi;Prescription of chinese material medica;Compound compatibility
[1] WANG Yi-tao(王一涛). World Science and Technology(世界科学技术), 1999, 1(2): 16. [2] CAO Feng, ZHOU Qun, SUN Su-qin(曹峰, 周群, 孙素琴). Modern Instruments(现代仪器), 2002, (4): 19. [3] SUN Su-qin, ZHOU Qun, LEUNG Hi-wun(孙素琴, 周群, 梁曦云). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2003, 23(6): 1082. [4] TANG Jun-ming,XIAN Dong,SUN Su-qin(汤俊明, 鲜栋, 孙素琴). Modern Instruments(现代仪器), 2005, (11): 27. [5] Lü Guang-hua,SUN Su-qin,LEUNG Hi-wun,et al(吕光华, 孙素琴, 梁曦云, 等). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2004, 24(3): 311. [6] Nation Significance Effort “Modern Studie of Several Key Scientific Task in Chinese Materia Medica” 2007 Year Fund Item Application Guide, The State Natural Science Foundation of China(《中医药学几个关键科学问题的现代研究》重大研究计划2007年度基金项目申请指南,国家自然科学基金委员会). [7] CAO Hong-xin(曹洪欣). The Foundation Theory in Traditional Chinese Medicine(中医理论基础). Beijing: Traditional Chinese Medicine Press(北京: 中国中医出版社),2004. 8. [8] Sielsler H W,Ozaki Y,Kawatas,et al. Near-Infrared Spectroscopy:Principles,Instruments,Applications. West Sussex:NIR Publications,2002. [9] Ciurczak E W,Drennen J K. Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy. New York:Arcel Dekker Inc,2002. [10] CHEN Hua-cai, CHEN Xing-dan(陈华才, 陈星旦). Journal of China Jiliang University(中国计量学院学报), 2003, 14(4):261. [11] CHU Xiao-li, YUAN Hong-fu, LU Wan-zhen(褚小立, 袁洪福, 陆婉珍). Analytical Instrumentation(分析仪器), 2006, (2): 1. [12] LI Yan, WU Ran-ran, YU Bai-hua,et al(李燕, 吴然然, 于佰华, 等). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2006,26(10): 1846. [13] CAO Zhi-quan(曹治权). Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai(上海中医药大学学报), 2000,14(1): 36. [14] JIANG Da-cheng, WANG Yong-sheng, WENG Li-li, et al(姜大成,王永生,翁丽丽, 等). Spectral Identification of Traditional Chinese Medicine Commonly Used(常用中药光谱鉴定). Beijing:Chemical Industry Press(北京: 化学工业出版社), 2004. [15] LIANG Guo-gang(梁国刚). China Journal of Chinese Materia Medica(中国中药杂志),1999, 24(2): 67. [16] ZHU Shi-na(祝世讷). China Journal of Basic Medicine in Traditional Chinese Medicine(中国中医基础医学杂志), 2000, 6(11): 13.