Study on Real-Time Control of Extraction Procedure of Furitus Gardenia by Near Infrared Spectroscopy
YAN Shi-kai1,2, LUO Guo-an2*, WANG Yi-ming2, CHENG Yi-yu1
1. Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China 2. Department of Chemistry, Tsinghua University, Beijing 100084, China
Abstract：A new approach to the real-time control of extraction procedures based on fiber optic near infrared spectroscopy (NIR) was described. Various extraction samples of gardenia were rapidly scanned by NIR, and the SIMCA monitoring model was developed. The model was applied to evaluate the extraction procedures of 26 unknown samples, and all the samples from abnormal procedures were successfully identified. It is suggested that near infrared spectroscopy, combined with SIMCA method, is a rapid, convenient and efficient tool for real-time procedure monitoring, which needs no quantitative determination and can effectively monitor whether the current procedure is in normal or not. The presented approach, therefore, offers a new way for the quality control in real-time of traditional Chinese medicine.
Key words：Furitus gardenia;Near infrared spectroscopy;SIMCA;Real-time control
严诗楷1，2,罗国安2*,王义明2,程翼宇1 . 栀子药材提取工艺的近红外光谱实时控制方法研究[J]. 光谱学与光谱分析, 2006, 26(06): 1026-1030.
YAN Shi-kai1,2, LUO Guo-an2*, WANG Yi-ming2, CHENG Yi-yu1 . Study on Real-Time Control of Extraction Procedure of Furitus Gardenia by Near Infrared Spectroscopy. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(06): 1026-1030.
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