1. Analysis and Testing Center, Nanjing Normal University, Jiangsu Engineering Research Center of Bio-Medical Function Materials, Nanjing 210097, China 2. College of Chemistry and Environment Science, Nanjing Normal University, Nanjing 210097, China 3. Technical Institute of Piysics and Chemistry, Chinese Academy of Sciences, Beijing 100101, China
Abstract：The effects of hypocrellin A (HA) on the conformational changes of hemoglobin and myoglobin were studied using synchronous fluorescence spectroscopy. The results indicated that HA can change the conformation of these two proteins，leading to the change in the micro-environment of tryptophane and tyrosine residues from hydrophobic environment to hydrophilic environment to different extent.
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