Microscopic Hyperspectral Image Study of Normal and Diabetic Retina Tissues of Rats
LI Qing-li1,XUE Yong-qi2,ZHANG Jing-fa3,LIU Zhi1
1. Department of Automation,Shanghai Jiaotong University,Shanghai 200030,China 2. Institute of Technical Physics,Chinese Academy of Sciences,Shanghai 200083,China 3. Institute of Health,Shanghai Jiaotong University,Shanghai 200030,China
Abstract:A microscopic hyperspectral imaging device was used to study the normal and diabetic retinas of rats. The microscopic hyperspectral images of retinas from normal,diabetic and medicative rats were collected and processed. Some transmission spectral curves of outer nuclear layer of retina were extracted and analyzed. The results showed that there are three characteristic spikes in the spectral curves between 400 and 800 nm from the outer nuclear layer,and the heights of the characteristic spikes at 113 band were altered obviously between the normal and diabetic retinas. In addition,the spectral curve of the diabetic retina changes gradually to the normal spectrum curve after treatment by the LCVS1001. The experiment result showed that the microscope hyperspectral imaging device could be used to study the changes in spectrum characters and physical chemistry composition of the diabetic retina.
李庆利1,薛永祺2,张敬法3,刘治1 . 糖尿病与正常大鼠视网膜组织显微高光谱图像数据研究[J]. 光谱学与光谱分析, 2007, 27(08): 1603-1606.
LI Qing-li1,XUE Yong-qi2,ZHANG Jing-fa3,LIU Zhi1. Microscopic Hyperspectral Image Study of Normal and Diabetic Retina Tissues of Rats. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(08): 1603-1606.