光谱学与光谱分析 |
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Current Status and Recent Advances in Research and Application of THz Technology in Articular Cartilage Detection |
MA Yu-ting1,2, ZHANG Jin1, SHI Chang-cheng2*, LI Wei2, HAN Xiao-hui1, PENG Xiao-yu2, WEI Dong-shan2, DU Chun-lei2, CUI Hong-liang1,2* |
1. College of Instrumentation & Electrical Engineering, Jilin University,Changchun 130061,China 2. Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Research Center for Terahertz Technology, Chongqing Key Laboratory of Multi-scale Manufacturing Technology, Chongqing 400714,China |
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Abstract Osteoarthritis is a common arthritis disease caused by cartilage tissue damage and degeneration, which is one of the large epidemics that affect human health. The early detection of the pathological changes of articular cartilage can greatly improve the cure rate of disease, but the relevant clinical diagnosis technology has not been developed. In recent years, the applications and researches of terahertz technology are increasingly valued and it has drawn great attention in the field of medicine. Compared with traditional methods, the terahertz radiation is low-energy and non-ionizing whose spectral-fingerprinting capability is well-known in the biological world. Meanwhile, THz technology has a great potential in diagnosis of articular cartilage early degeneration. This paper briefly introduces the physiological and pathological conditions of the articular cartilage, the current clinical techniques of articular cartilage detection. It mainly summarizes the terahertz technology used for detecting articular cartilage, including detection of animal and human cartilage respectively. At last, the challenges and development prospects of terahertz technology in articular cartilage detection are discussed.
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Received: 2015-05-21
Accepted: 2015-09-26
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Corresponding Authors:
SHI Chang-cheng, CUI Hong-liang
E-mail: ccshi@cigit.ac.cn; hcvi@jlu.edu.cn
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