| 光谱学与光谱分析 |
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| The Development and Applications of Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionization |
| HUANG Zheng-xu1, GUO Chang-juan1, CHEN Hua-yong1, ZHOU Zhen1,2* |
1. Guangzhou Institute of Geochemistry, Chinese Academy of Sciences,State Key Laboratory of Organic Geochemistry, Guangzhou 510640, China
2. Institute of Environmental Pollutant and Health, School of Environment and Chemical Engineering, Shanghai University, Shanghai 200027, China |
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Abstract A kind of new ionization source, atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI), is introduced in the present paper. This ionization source was studied and developed on the basis of vacuum MALDI. It has been applied widely in the field of biomacromolecule. This ionization source has softer analyte ionization and produces fewer fragmentations compared with conventional vacuum MALDI. It works at atmospheric pressure, therefore eases to be coupled to mass spectrometers, acting as an external ion source, and greatly extends the application fields of MALDI. The principle, configuration and technical development of AP-MALDI are described detailedly. Moreover, the current applications and prospect of the device in analyzing biopolymers are summarized.
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Received: 2006-06-16
Accepted: 2006-10-28
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Corresponding Authors:
ZHOU Zhen
E-mail: zhouzhen@gig.ac.cn
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| Cite this article: |
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HUANG Zheng-xu,GUO Chang-juan,CHEN Hua-yong, et al. The Development and Applications of Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionization[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(10): 1910-1916.
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| URL: |
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https://www.gpxygpfx.com/EN/Y2007/V27/I10/1910 |
[1] Fenn J B, et al. Proc. 36th Ann. Conf. Am. Soc. MS., San Francisco, 5-10, June, 1988. 773.
[2] Tanaka K, et al. Proc. 2nd Japan-China Joint Symp. on MS., Osaka, Jpn, 15-18, Sept. 1987. 185.
[3] Loboda A V, Krutchinsky A N, Bromirski M, et al. Rapid Commun. Mass Spectrom., 2000, 14: 1047.
[4] Laiko V V, Burlingame A L. U.S. Patent, 5965884, 1999.
[5] HE Mei-yu, HE Jiang-tao(何美玉, 何江涛). Journal of Chinese Mass Spectrometry Society(质谱学报), 2002, 23(1): 43.
[6] LIU Shan(刘 珊). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2003, 23(4): 829.
[7] LI Yong-min(李永民). Analysis and Testing Technology of Instruments(分析测试技术与仪器), 2002, 8(3):131.
[8] Laiko V V, Moyer S C, and Cotter R J. Anal. Chem., 2000, 72: 5239.
[9] Doroshenko V M, Laiko V V, Taranenko N I, et al. Int. J. Mass Spectrom., 2002, 221: 39.
[10] Danell R M, Glish G L. Proc. 48th ASMA Conf. on MS and AT, American Society of Mass Spectrometry Long Beach CA, 2000.
[11] Galicia M C, Vertes A, Callahan J H. Anal. Chem., 2002, 74: 1891.
[12] Overberg A, Karas M, Bahr U, et al. Rapid Commun. Mass Spectrom., 1990, 4: 293.
[13] Laiko V V, Taranenko N I, Berkout V D, et al. J. Am. Soc. Mass Spectrom., 2002, 13: 354.
[14] Mclean J A, Russell W K, Russell D H. Anal. Chem., 2003, 75: 648.
[15] Lin B, Sunner J. J. Am. Soc. Mass Spectrom., 1994, 5: 873.
[16] Shaffer S A, Prior D C, Anderson G A, et al. Anal. Chem., 1998, 70: 4111.
[17] Shaffer S A, Tolmachev T, Prior D C, et al. Anal. Chem., 1999, 71: 2957.
[18] Tan P V, Laiko V V, Doroshenko V M. Anal. Chem., 2004, 76: 2462.
[19] Dodonov A F, Chernushevich L V, Laiko V V. Time-of-Flight Mass Spectrometry. ACS Symposium Series 549, Washington DC: American Chemical Society, 1994, Chapter 7.
[20] Moyer S C, Cotter R J, Woods A S. Am. Soc. Mass Spectrom., 2002, 13: 274.
[21] Moyer S C, Cotter R J. Anal. Chem., 2002, 74(17): 469A.
[22] Moyer S C, VonSeggern C E, Cotter R J. Am. Soc. Mass Spectrom., 2003, 14: 581.
[23] Levander F, James P. Journal of Proteome Research, 2005, 4: 71.
[24] Seggern C E V, Moyer S C, Cotter R J. Anal. Chem., 2003, 75: 3212.
[25] Madonna A J, Voorhees K J, Taranenko N I, et al. Anal. Chem., 2003, 75: 1628.
[26] Pribil P A, Patton E, Black G, et al. J. Am. Soc. Mass Spectrom., 2005, 16: 464.
[27] Laiko V V, Baldwin M A, Burlingame A L. Anal. Chem., 2000, 72: 652.
[28] Schneider B B, Lock C, Covey T R. Am. Soc. Mass Spectrom., 2005, 16: 176.
[29] Kellersberger K A, Yu E T, Merenbloom S I, et al. Am. Soc. Mass Spectrom., 2005, 16: 199.
[30] Seggern C E V, Cotter R J. J. Am. Soc. Mass Spectrom., 2003, 14: 1158.
[31] Zhang J H, Lamotte L, Dodds E D, et al. Anal. Chem., 2005, 77: 4429.
[32] Cui M, McCooeye M A, Fraser C, et al. Anal. Chem., 2004, 76: 7143.
[33] Strategic Directions International, Inc. Mass Spectrometry Market Analysis and Perspectives Report. October 2005.
[34] ZHAO Shu-rui, CHEN Jin-zhong, WEI Yan-hong, et al(赵书瑞，陈金忠，魏艳红，等). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2004, 24(2): 214. |
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