| 光谱学与光谱分析 |
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| Study on Transient Absorption Spectrum of Tungsten Nanoparticle with HepG2 Tumor Cell |
| CAO Lin1, SHU Xiao-ning1, LIANG Dong1, WANG Cong2 |
1. School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China
2. The Hong Kong University of Science & Technology, Hong Kong, China |
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Abstract Significance of this study lies in tungsten nano materials can be used as a preliminary innovative medicines applied basic research .This paper investigated the inhibition of tungsten nanoparticles which effected on human hepatoma HepG2 cells by MTT. The authors use transient absorption spectroscopy (TAS) technology absorption and emission spectra characterization of charge transfer between nanoparticles and tumor cell. The authors discussed the role of the tungsten nanoparticles in the tumor early detection of the disease and its anti-tumor properties. In the HepG2 experiments system,100～150 μg·mL-1 is the best drug concentration of anti-tumor activity which recact violently within 6 hours and basically completed in 24 hours. The results showed that transient absorption spectroscopy can be used as tumor detection methods and characterization of charge transfer between nano-biosensors and tumor cells. Tungsten nanoparticles have potential applications as anticancer drugs.
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Received: 2013-08-21
Accepted: 2014-01-29
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Corresponding Authors:
CAO Lin
E-mail: lincaoustb@sina.com
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[1] Raynaud M，Chermann J C，Plata F，et al. Inhibiteurs Des Virus du Groupe Leucrmie-Sarcomes Murins. Silico-Tungstate. Paris：Comptes RenDus Hebdomedaire Des Seances De l’Acaddmie Des Sciences，1971. 272，347.
[2] Yamase T，Fujita H，Fukushima K. Inorganica Chimica Acta，1988，151：15.
[3] CHEN Liang-dong, LI Yan, YUAN Hong-yin, et al(陈良冬, 李 雁，袁宏银，等). Chnese Journal of Cancer(癌症), 2006, 25(5)：651.
[4] HAO Lan, WANG Zhi-gang(郝 兰, 王志刚). Journal of Clinical Ultrasound in Medicine(临床超声医学杂志), 2013, (03).
[5] Cao Lin, Yang Fuqiang, Cao Jiexin. International Journal of Minerals, Metallurgy and Materials, 2009, 16(4): 468.
[6] Cao Lin, Cao Jiexin, Wang Cong, et al. Bull. Mater. Sci., 2012, 35(5): 767.
[7] ZHAO Jie, CAO Lin(赵 婕, 曹 林). Journal of University of Science and Technology(北京科技大学学报), 2007, 29(7)：730.
[8] CHEN Gui-fang, LIANG Zhi-qiang, LI Gen-xi(陈桂芳，梁志强，李根喜). Acta Biophysica Sinica(生物物理学报)，2010, 26(8): 711. |
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