| 光谱学与光谱分析 |
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| Method of Fast and Automated Detection of Diabetic Retinopathy Based on Mathematical Morphology |
| GAO Wei-wei, SHEN Jian-xin, WANG Yu-liang |
| College of Mechanical & Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China |
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Abstract The technology of automated detection of diabetic retinopathy (DR) on fundus retinal images can not only make mass screening possible, but also offer a powerful adjunct for early diagnosis, treatment of diabetic retinopathy, and scientific research on human vision. For this purpose, an algorithm based on mathematical morphology for automated detection of diabetic retinopathy was proposed. Firstly, the optic disc was segmented by mathematical morphology and threshold in order to find candidate regions possibly containing lesions. Secondly, some methods such as morphological reconstruction were applied to find the exact contours of lesions. Finally, the true lesions were found out exactly. Experimental results showed that the algorithm was fast and effective in detecting diabetic retinopathy of fundus retinal images.
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Received: 2011-07-03
Accepted: 2011-10-28
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Corresponding Authors:
GAO Wei-wei
E-mail: gww03020234@sina.com
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[1] LIU Wei, ZHANG Yong-jin(刘 卫, 张勇进). Section Ophthalmol Foreign Med. Sci.(国外医学眼科学分册), 2005, 29(5): 352.
[2] Ong G L, Ripley L G, et al. Am. J. Ophthalmol, 2004, 17: 445.
[3] SU Lian-rong, LI Qi(苏连荣, 李 琦). International Journal of Ophthalmology(国际眼科杂志), 2009, 9(8): 1526.
[4] Ward N P, Tomlinson S, Taylor C J. Ophthalmal，1989，96(1)：80.
[5] Osareh A, Mirmehdi M, Thomas B, et al. Proc. Medical Image Understanding Analysis Conf., 2001. 49.
[6] Sinthanayothin C, Boyce J F, Williamson T H, et al. Diabetic Medicine, 2002, 19: 105.
[7] Meindert Niemeijer, Bram van Ginneken, Stephen R. Russell. Investigative Ophthalmology & Visual Science, 2007, 48(5): 2260.
[8] ZHOU Hao, LI Yun, ZHOU Yun-qiu, et al(周 浩，李 云，周韵秋, 等). J. Biomed. Eng.(生物医学工程杂志), 1999, 16(3): 318.
[9] XU Li-li, LIU Lei, DING Ku-ke, et al(许莉莉, 刘 磊, 丁库克, 等). Computer Applications and Software(计算机应用与软件), 2009, 26(11): 127.
[10] LI Chun-fang, DING Xiao-yan(李春芳, 丁小燕). New Medicine(新医学), 2004, 35(1): 10.
[11] Massin P, Erginay A, Gaudric A. Rétinopathie Diabéthique. Paris, France: Elsevier, 2000, 1.
[12] CUI Yi(崔 屹). Image Processing and Analysis—the Methods of Mathematical Morphological and Its Application(图像处理与分析—数学形态学方法及应用). Beijing: Science Press(北京: 科学出版社), 2000.
[13] Lü Fan, XU Liang(吕 帆, 徐 亮). Device of Ituman Eys Optics(眼视光器械学). Beijing: People’s Medical Publishing House(北京: 人民卫生出版社), 2004.
[14] Sa′ nchez C I, Hornero R, Lo′ pez M I, et al. Med. Eng. Phys., 2007, 30: 350.
[15] British Diabetic Association. Retinal Photography Screening for Diabetic Eye Disease. London: British Diabetic Association, 1997. |
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