H3O+,NO+和O+·2离子同九种烷氧基醇化合物反应的研究

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Abstract Following a selected ion flow tube mass spectrometry(SIFT-MS), analysis of the headspace of a commercial available nail polish remover pad in which γ-butyrolactone (GBL) and 2-butoxy-1-ethanol were found to be the major volatiles, a study of the reactions of H₃O⁺,NO⁺ and O^+·₂ ions with nine alkoxy alcohols (R₁—O—R₂OH) was carried out using selected ion flow tube(SIFT) at a carrier gas (helium) pressure of 9.3×10¹ Pa. Experiments were also performed at various carrier gas pressures (4×10¹-1.1×10² Pa) for some reactions and under moist air condition. The number and distribution of the hydrates for the product ions were used to identify their structures and to investigate reaction mechanisms. The H₃O⁺ reactions proceed via nascent ion-molecule complex (H₃O⁺.M)^*,then produce R₁—O—R₂OH.H⁺,(R₁—O—R₂)⁺,HOR₂OH.H⁺ and R₂O.H⁺ ions through various channels. Similarly, via a nascent complex (NO⁺.M)^*, NO⁺.M,(M—H)⁺ and (M—ROH)⁺ ions were produced in the NO⁺ reactions. The collisions between the nascent complexes (H₃O⁺.M)^* and (NO⁺.M)^* with a third body (He, N₂ and O₂ etc) have influence on the product ion distributions. The O^+·₂ reactions produce mainly dissociative product ions and it is uncertain whether they proceed via the nascent ion-molecule complex (O^+·₂.M)^*. This study provides rate coefficients and product ions in the SIFT-MS database for the analysis of these compounds in normal and humid air samples. It will be further utilised into addiction and drug abuse, respiratory medicine and other research areas using SIFT-MS.

Key words：SIFT;SIFT-MS;Mechanism;Nascent ion-molecule complex;Volatile;Biomarker

Received: 2005-12-15 Accepted: 2005-12-20

ZTFLH:

O657.5

Corresponding Authors: Tianshu WANG

Cite this article:

Tianshu WANG. A Study of the Reactions of H₃O⁺,NO⁺ and O^+·₂ Ions with Nine Alkoxy Alcohols[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(04): 747-752.

URL:

https://www.gpxygpfx.com/EN/Y2006/V26/I04/747

[1] Sabourin P J, Medinsky M A, Birnbaum L S, Griffith W C, Henderson R F. Toxicol. Appl. Pharmacol., 1992, 114: 232.
[2] Romer K G, Balge F, Freundt K J. Drug Chem. Toxicol., 1985, 8: 255.
[3] Bloor R, Wang T S, paněl P, Smith D. Applications of Selected Ion Flow Tube Mass Spectrometry(SIFT-MS), in Addiction Research. in Amman A, Smith D. (Eds.), Breath Analysis for Clinical Diagnosis and Therapeutic Monitoring, World Scientific, Singapore, 2005, 409.
[4] Carroll W, Lenney W, Wang T S, Spaněl P, A. Alcock, Smith D. Pediatric Pulmonology, 2005, 39: 452.
[5] Harrison A G. Chemical Ionization Mass Spectrometry. Boca Raton: CRC Press, 1992.
[6] Lindinger W, Hansel A, Jordan A. Int. J. Mass Spectrom. Ion Process, 1998, 173: 191.
[7] Custer T G, Kato S, Fall R, Bierbaum V M. Int. J. Mass Spectrom., 2003, 223/224: 427.
[8] Smith D, Spaněl P . Mass Spectrom. Rev., 2005, 24: 661.
[9] Adams N G, Smith D. Int. J. Mass Spectrom. Ion Phys., 1976, 21: 349.
[10] Dryahina K, Polasek M, Spaněl P. Int. J. Mass Spectrom., 2004, 239: 57.
[11] Michel E, Schoon N, Amelynck C, Guimbaud C, Catoire V, Arijs E. Int. J. Mass Spectrom., 2005, 244: 50.
[12] Davis B M, Senthilmohan S T, Wilson P F, McEwan M J. Rapid Commun. Mass Spectrom., 2005, 19: 2272.
[13] Jackson D M, Stibrich N J, Adams N G, Babcock L M. Int. J. Mass Spectrom., 2004, 243: 115.
[14] Davies S J, Spaněl P, Smith D. J. Am. Soc. Nephrol., 1996, 7: 1316.
[15] WANG Tian-shu(王天舒). Chinese J. Anal. Chem.(分析化学), 2005, 33: 887.
[16] Wang T S, Spaněl P, Smith D. Int. J. Mass Spectrom., 2004, 237: 167.
[17] Wang T S, Spaněl P, Smith D. A Comparative Study of Breath Ethanol and HDO Using SIFT-MS and FA-MS: Ethanol Metabolism and Total Body Water. Abstract in the Conference “Breath Gas Analysis for Medical Diagnostics”, Dornbirn Austria, Sept 23-26: 2004.
[18] Su T, Chesnavich W J. J. Chem. Phys., 1982, 76: 5183.
[19] Lide D R(Ed.), CRC Handbook of Chemistry and Physics, CRC, Boca Raton, 1991.
[20] Wang T S, Carroll W, Lenney W, Boit P, Smith D. Rapid Commun. Mass Spectrom., 2006, 20: 125.
[21] Spaněl P, Smith D. Int. J. Mass Spectrom. Ion Processes, 1998, 172: 239.
[22] Spaněl P, Smith D. Int. J. Mass Spectrom. Ion Processes, 1997, 167/168: 375.
[23] Spaněl P, Doren J M V, Smith D. Int. J. Mass Spectrom., 2002, 213: 163.
[24] Spaněl P, Wang T S, Smith D. Int. J. Mass Spectrom., 2002, 218: 227.
[25] Smith D, Wang T S, Spaněl P. Int. J. Mass Spectrom., 2003, 230: 1.
[26] Carroll W. Clinical Observation, Private Communication.
[27] Lias S G. in: Mallard W G, Linstrom P J (Eds.) NIST Standard Reference Database Number 69, National Institute of Standards and Technology, Gaithersburg, MD, 2000.