| 光谱学与光谱分析 |
|
|
|
|
|
| Characteristics Analysis of the Thyroid Gland Surface of Normal Human with Fourier Transform Infrared (FTIR) Spectra |
| WU Min, ZHANG Wei-tao, TIAN Pei-rong, LING Xiao-feng, XU Zhi* |
| Department of General Surgery, Peking University Third Hospital, Beijing 100191, China |
|
|
|
|
Abstract In order to obtain 240 cases of the surface Fourier transform infrared (FTIR) spectra of normal human thyroid gland, 120 healthy volunteers were enrolled in this study and scanned by using two mid-infrared optical fibers equipped with an attenuated total reflectance (ATR) to probe through the skin of two lobes of thyroid gland. Then whether there were differences between the surface FTIR spectra of the right lobe and that of the left part of the normal human thyroid gland was explored by comparing the 35 variables of 12 bands, including peak positions, relative intensity ratios and full width at half maximum of FTIR spectrums. Also the spectra characteristics of unique absorbent bands that represent changes of structure and quantity of variance biochemical substances such as nucleic acids, proteins and carbohydrates were illustrated. Results indicated that the surface FTIR spectra of the right part and that of the left part of the normal human thyroid gland were generally coincided, with statistically significant differences in four spectrum parameters, includingF1 640, P2 920, P1 040 and I2 920/I1 460. A series of data about the 90% normal reference range of the unique spectrum parameters in the surface FTIR spectra of normal human thyroid gland was gained, and a standard average infrared spectrogram which can fully represent the basic features of normal human thyroid gland was plotted. The conclusions above could be used as a reference for clinical diagnosis of thyroid diseases with FTIR spectroscopy.
|
|
Received: 2015-06-23
Accepted: 2015-11-08
|
|
|
|
Corresponding Authors:
XU Zhi
E-mail: xuzhi123456@sohu.com
|
|
[1] Mantsch H, Chapman D. Infrared Spectroscopy of Biomolecules, New York, John Wiley &Sons Inc., 1996. 1.
[2] WENG Shi-fu(翁诗甫). Fourier Transform Infrared Spectroscopy Analysis(傅里叶变换红外光谱分析). Beijing: Chemical Industry Press(北京：化学工业出版社), 2010. 337.
[3] ZHAO Jin, LIU Ya-qi, XU Yi-zhuang, et al(赵 谨，刘亚奇). Chem. J. Chinese Universities(高等学校化学学报), 2011, 25(2): 246.
[4] Liu Dong, Xuejun Sun, Zhang Chao, et al. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014, 25(122): 288.
[5] LIN Zhong-ming, XU Le, XU Wen-ping, et al(林宗明，许 乐，许文平，等). Chinese Journal of Clinical Medicine(中国临床医学), 2008, 15(6): 854.
[6] XU Yi-zhuang, ZHAO Yin, XU Zhi, et al(徐怡庄，赵 莹，徐 智，等). Chem. J. Chinese Universities(高等学校化学学报), 2005, 26(12): 2227.
[7] Tong Yiping, Lin Yuanwen, Xiao Yulong, et al. Analytical Chemistry, 2002, 30(06): 726.
[8] Lisa M Miller, Megan W Bourassa, Randy J. Smith. BBA—Biomembranes, 2013, 1828(10): 2339.
[9] Liu Lunming, Ji Yong, Tang Weiyue, et al. Journal of Basic and Clinical Oncology, 2006, 19(2): 99.
[10] Zhang Xiaoqing, Xu Yizhuang, Zhang Yuanfu, et al. Journal of Surgical Research, 2011, 171(2): 650.
[11] Zhang Weitao, Tian Peirong, Zhu Qing, et al. Chemical Research in Chinese Universitis, 2015, 31(2): 198. |
| [1] |
GUO Ya-fei1, CAO Qiang1, YE Lei-lei1, ZHANG Cheng-yuan1, KOU Ren-bo1, WANG Jun-mei1, GUO Mei1, 2*. Double Index Sequence Analysis of FTIR and Anti-Inflammatory Spectrum Effect Relationship of Rheum Tanguticum[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 188-196. |
| [2] |
TIAN Ze-qi1, WANG Zhi-yong1, YAO Jian-guo1, GUO Xu1, LI Hong-dou1, GUO Wen-mu1, SHI Zhi-xiang2, ZHAO Cun-liang1, LIU Bang-jun1*. Quantitative FTIR Characterization of Chemical Structures of Highly Metamorphic Coals in a Magma Contact Zone[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(09): 2747-2754. |
| [3] |
ZHANG Xiao-xu1, LIN Xiao-xian3, ZHANG Dan2, ZHANG Qi1, YIN Xue-feng2, YIN Jia-lu3, 4, ZHANG Wei-yue4, LI Yi-xuan1, WANG Dong-liang3, 4*, SUN Ya-nan1*. Study on the Analysis of the Relationship Between Functional Factors and Intestinal Flora in Freshly Stewed Bird's Nest Based on Fourier Transform Infrared Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(08): 2452-2457. |
| [4] |
WANG Bin1, 2, ZHENG Shao-feng2, GAN Jiu-lin1, LIU Shu3, LI Wei-cai2, YANG Zhong-min1, SONG Wu-yuan4*. Plastic Reference Material (PRM) Combined With Partial Least Square (PLS) in Laser-Induced Breakdown Spectroscopy (LIBS) in the Field of Quantitative Elemental Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(07): 2124-2131. |
| [5] |
WANG Yu-hao1, 2, LIU Jian-guo1, 2, XU Liang2*, DENG Ya-song2, SHEN Xian-chun2, SUN Yong-feng2, XU Han-yang2. Application of Principal Component Analysis in Processing of Time-Resolved Infrared Spectra of Greenhouse Gases[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(07): 2313-2318. |
| [6] |
SU Ling1, 2, BU Ya-ping1, 2, LI Yuan-yuan2, WANG Qi1, 2*. Study on the Prediction Method of Pleurotus Ostreatus Protein and
Polysaccharide Content Based on Fourier Transform Infrared
Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(04): 1262-1267. |
| [7] |
ZHOU Ao1, 2, YUE Zheng-bo1, 2, LIU A-zuan1, 2, GAO Yi-jun3, WANG Shao-ping3, CHUAI Xin3, DENG Rui1, WANG Jin1, 2*. Spectral Analysis of Extracellular Polymers During Iron Dissimilar
Reduction by Salt-Tolerant Shewanella Aquimarina[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(04): 1320-1328. |
| [8] |
FENG Yu, ZHANG Yun-hong*. Rapid ATR-FTIR Principal Component Analysis of Commercial Milk[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(03): 838-841. |
| [9] |
YUE Kong, LU Dong, SONG Xue-song. Influence of Thermal Modification on Poplar Strength Class by Fourier Infrared Spectroscopy Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(03): 848-853. |
| [10] |
ZHANG Yan1, 2, WANG Hui-le1, LIU Zhong2, ZHAO Hui-fang1, YU Ying-ying1, LI Jing1, TONG Xin1. Spectral Analysis of Liquefaction Residue From Corn Stalk Polyhydric
Alcohols Liquefaction at Ambient Pressure[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(03): 911-916. |
| [11] |
QIAO Lu1, LIU Rui-na1, ZHANG Rui1, ZHAO Bo-yu1, HAN Pan-pan1, 2, ZHOU Chun-ya1, 3, ZHANG Yu-qing1, 4, DONG Cheng-ming1*. Analysis of Spectral Characteristics of Soil Under Different Continuous Cropping of Rehmannia Glutinosa Based on Infrared Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(02): 541-548. |
| [12] |
CHEN Yong1, 2, GUO Yun-zhu1, WANG Wei3*, WU Xiao-hong1, 2*, JIA Hong-wen4, WU Bin4. Clustering Analysis of FTIR Spectra Using Fuzzy K-Harmonic-Kohonen Clustering Network[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(01): 268-272. |
| [13] |
PAN Han-jiang, GU Tie-xin, LIU Mei, YANG Rong*, ZHAO Kai, GU Xue. Research Progress and Design on Reference Materials of Atmospheric Particulates[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(12): 3659-3664. |
| [14] |
HU Yun-you1, 2, XU Liang1*, XU Han-yang1, SHEN Xian-chun1, SUN Yong-feng1, XU Huan-yao1, 2, DENG Ya-song1, 2, LIU Jian-guo1, LIU Wen-qing1. Adaptive Matched Filter Detection for Leakage Gas Based on Multi-Frame Background[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(10): 3307-3313. |
| [15] |
JING Jian-yuan, YUAN Liang, ZHANG Shui-qin, LI Yan-ting, ZHAO Bing-qiang*. Multispectral Structural Characterization of Humic Acid-Enhanced Urea[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2022, 42(08): 2610-2615. |
|
|
|
|
