光谱学与光谱分析 |
|
|
|
|
|
Studies of Male Fertility with Raman Spectroscopy |
HUANG Zu-fang1*, CAO Gang1, SUN Yan2, DU Sheng-rong2, LI Yong-zeng1, LIN Ju-qiang1, FENG Shang-yuan1, LEI Jin-ping1 |
1. Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou 350007, China 2. Fujian Maternal and Child Health Hospital, Fuzhou 350001, China |
|
|
Abstract Raman spectroscopy which belongs to scattering spectroscopy obtained molecular vibrational and rotational information to achieve detection and analysis of molecular structure and corresponding changes through recording the frequency shift when light interacted with materials. Compared with routine biochemical analysis, Raman spectroscopy has the advantage of non-invasive, label-free and no sample requirement. Raman spectroscopy has been widely applied in biomedical field such as human tissue, organs, cells and human body fluids for disease diagnosis. This article mainly focuses on recent research advances of Raman spectroscopy in human semen. Firstly, Raman spectroscopy(including surface-enhanced Raman spectroscopy, SERS) employed in forensic science for semen analysis, and some related data processing methods were introduced, then Raman spectroscopy involved investigations of male fertility was highlighted, more specifically, the Raman-based qualitative and quantitative analysis which assist the objective detection and evaluation of male fertility. Furthermore, studies of single sperm cell based on micro-Raman system to characterize and evaluate sperm quality and the preliminarily obtained Raman biomarkers which indicate high-quality sperm cell were introduced. Finally, the potential development of Raman spectroscopy involved in reproduction and fertility field was also discussed.
|
Received: 2015-06-11
Accepted: 2015-11-05
|
|
Corresponding Authors:
HUANG Zu-fang
E-mail: zfhuang@fjnu.edu.cn
|
|
[1] YI Wei-song, JIANG Hou-min(易伟松,江厚敏). Acta Laser Biology Sinica(激光生物学报), 2011, 20(2): 280. [2] Rohleder D, Kiefer W, Petrich W. Analyst, 2004, 129(10): 906. [3] Inscore F, Shende C, Sengupta A. Applied Spectroscopy, 2011, 65(9): 1004. [4] Yuen C, Zheng W, Huang Z. Biosensors and Bioelectronics, 2010, 26(2): 580. [5] Feng S, Lin D, Lin J. Analyst, 2013, 138(14): 3967. [6] Li Y, Pan J, Chen G. Journal of Biomedical Optics, 2013, 18(2): 027003. [7] Chen P, Tian Q, Baek S. Laser Physics Letters, 2011, 8(7): 547. [8] Feng S, Chen R, Lin J. Biosensors and Bioelectronics, 2010, 25(11): 2414. [9] Virkler K, Lednev I K. Forensic Science International, 2009, 193(1): 56. [10] Sikirzhytski V, Sikirzhytskaya A, Lednev I K. Forensic Science International, 2012, 222(1): 259. [11] Huang Z, Chen X, Li Y. Applied Spectroscopy, 2013, 67(7): 757. [12] Huang Z, Wang J, Lin J. Journal of Raman Spectroscopy, 2014, 45(10): 879. [13] Huang Z, Chen X, Chen Y. Journal of Biomedical Optics, 2011, 16(11): 110501. [14] Chen X, Huang Z, Feng S. International Journal of Nanomedicine, 2012, 7: 6115. [15] Belokopytova I A, Kostyleva E I, Tomilin A N. Molecular Reproduction and Development, 1993, 34(1): 53. [16] Blanchard Y, Lescoat D, Lannou D. Andrologia, 1990, 22(6): 549. [17] Bach O, Glander H J, Scholz G. Andrologia, 1990, 22(3): 217. [18] Meister K, Schmidt D A, Bründermann E. Analyst, 2010, 135(6): 1370. [19] Sánchez V, Redmann K, Wistuba J. Fertility and Sterility, 2012, 98(5): 1124. [20] Liu F, Zhu Y, Liu Y. Fertility and Sterility, 2013, 99(3): 684. [21] Huang Z, Chen G, Chen X. Journal of Biophotonics, 2014, 7(9): 671. |
[1] |
LI Jie, ZHOU Qu*, JIA Lu-fen, CUI Xiao-sen. Comparative Study on Detection Methods of Furfural in Transformer Oil Based on IR and Raman Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 125-133. |
[2] |
WANG Fang-yuan1, 2, HAN Sen1, 2, YE Song1, 2, YIN Shan1, 2, LI Shu1, 2, WANG Xin-qiang1, 2*. A DFT Method to Study the Structure and Raman Spectra of Lignin
Monomer and Dimer[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 76-81. |
[3] |
XING Hai-bo1, ZHENG Bo-wen1, LI Xin-yue1, HUANG Bo-tao2, XIANG Xiao2, HU Xiao-jun1*. Colorimetric and SERS Dual-Channel Sensing Detection of Pyrene in
Water[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 95-102. |
[4] |
WANG Xin-qiang1, 3, CHU Pei-zhu1, 3, XIONG Wei2, 4, YE Song1, 3, GAN Yong-ying1, 3, ZHANG Wen-tao1, 3, LI Shu1, 3, WANG Fang-yuan1, 3*. Study on Monomer Simulation of Cellulose Raman Spectrum[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 164-168. |
[5] |
WANG Lan-hua1, 2, CHEN Yi-lin1*, FU Xue-hai1, JIAN Kuo3, YANG Tian-yu1, 2, ZHANG Bo1, 4, HONG Yong1, WANG Wen-feng1. Comparative Study on Maceral Composition and Raman Spectroscopy of Jet From Fushun City, Liaoning Province and Jimsar County, Xinjiang Province[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2024, 44(01): 292-300. |
[6] |
LI Wei1, TAN Feng2*, ZHANG Wei1, GAO Lu-si3, LI Jin-shan4. Application of Improved Random Frog Algorithm in Fast Identification of Soybean Varieties[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3763-3769. |
[7] |
WANG Zhi-qiang1, CHENG Yan-xin1, ZHANG Rui-ting1, MA Lin1, GAO Peng1, LIN Ke1, 2*. Rapid Detection and Analysis of Chinese Liquor Quality by Raman
Spectroscopy Combined With Fluorescence Background[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3770-3774. |
[8] |
LIU Hao-dong1, 2, JIANG Xi-quan1, 2, NIU Hao1, 2, LIU Yu-bo1, LI Hui2, LIU Yuan2, Wei Zhang2, LI Lu-yan1, CHEN Ting1,ZHAO Yan-jie1*,NI Jia-sheng2*. Quantitative Analysis of Ethanol Based on Laser Raman Spectroscopy Normalization Method[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3820-3825. |
[9] |
LU Wen-jing, FANG Ya-ping, LIN Tai-feng, WANG Hui-qin, ZHENG Da-wei, ZHANG Ping*. Rapid Identification of the Raman Phenotypes of Breast Cancer Cell
Derived Exosomes and the Relationship With Maternal Cells[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3840-3846. |
[10] |
LI Qi-chen1, 2, LI Min-zan1, 2*, YANG Wei2, 3, SUN Hong2, 3, ZHANG Yao1, 3. Quantitative Analysis of Water-Soluble Phosphorous Based on Raman
Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(12): 3871-3876. |
[11] |
LIN Hong-jian1, ZHAI Juan1*, LAI Wan-chang1, ZENG Chen-hao1, 2, ZHAO Zi-qi1, SHI Jie1, ZHOU Jin-ge1. Determination of Mn, Co, Ni in Ternary Cathode Materials With
Homologous Correction EDXRF Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3436-3444. |
[12] |
GUO He-yuanxi1, LI Li-jun1*, FENG Jun1, 2*, LIN Xin1, LI Rui1. A SERS-Aptsensor for Detection of Chloramphenicol Based on DNA Hybridization Indicator and Silver Nanorod Array Chip[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3445-3451. |
[13] |
HUANG Li, MA Rui-jun*, CHEN Yu*, CAI Xiang, YAN Zhen-feng, TANG Hao, LI Yan-fen. Experimental Study on Rapid Detection of Various Organophosphorus Pesticides in Water by UV-Vis Spectroscopy and Parallel Factor Analysis[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3452-3460. |
[14] |
ZHU Hua-dong1, 2, 3, ZHANG Si-qi1, 2, 3, TANG Chun-jie1, 2, 3. Research and Application of On-Line Analysis of CO2 and H2S in Natural Gas Feed Gas by Laser Raman Spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3551-3558. |
[15] |
LIU Jia-ru1, SHEN Gui-yun2, HE Jian-bin2, GUO Hong1*. Research on Materials and Technology of Pingyuan Princess Tomb of Liao Dynasty[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 43(11): 3469-3474. |
|
|
|
|