Research on the Influence of Pressure-Induced Skin Deformation on the Diffuse Reflectance Spectra Measurement
LI Chen-xi1,2, JIANG Jing-ying2, LIU Rong1,2, CHEN Wen-liang1, 2*, XU Ke-xin1,2
1. State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin University, Tianjin 300072, China
2. School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China
Abstract：In the non-invasive tissue composition detecting, the diffuse reflectance spectroscopy could be affected by the measurement conditions, especially the tissue deformation induced by the contact pressure. In this paper, the physical model was simulated to quantify the changes of tissue thickness, optical properties and diffuse reflectance induced by the contact pressure, respectively. Firstly, based on the physical complex model and solid-liquid mixture composition of biological tissue, the deformation and changes of the water under contact pressure were quantitatively analyzed. In this model, the skin tissue was modeled as the elastic structure filled with Newtonian fluid. Then, the finite element method was applied to simulate the time-varying deformation of tissue under certain contact pressure. Secondly, the scattering and absorption coefficients of tissue were calculated with the quantitative results of the deformation and water migration in the three-layered skin tissue. After that, Monte Carlo method was used to simulate the light propagation within the tissue under different pressures. Finally, the effective information contained in the diffuse reflectance spectrum was analyzed to quantify the influence of the contact pressure. The results showed that the reduction of thickness and water content in dermis resulted in the decrease of effective information contained in the diffuse reflectance spectrum. The conclusions of this paper are beneficial for optimizing measurement strategy and improving accuracy and repeatability of the in vivo diffuse spectroscopy measurements.
李晨曦，蒋景英，刘 蓉，陈文亮，徐可欣. 接触压力作用下皮肤形变对于漫反射光谱测量影响研究[J]. 光谱学与光谱分析, 2017, 37(10): 3006-3010.
LI Chen-xi, JIANG Jing-ying, LIU Rong, CHEN Wen-liang, XU Ke-xin. Research on the Influence of Pressure-Induced Skin Deformation on the Diffuse Reflectance Spectra Measurement. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2017, 37(10): 3006-3010.
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