Preparation of Gold Nano-Particles as Surface-Enhanced Raman Scattering Sensors for Analysis of Banned Food Dye Chrysoidin in Yuba
XU Xue-qin1, LIU Qiong-hua1, YANG Fang2*, QIAN Jiang2, CHEN Jian2, LIN Zhen-yu1, QIU Bin1
1. MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou 350108, China 2. Fujian Provincial Key Laboratory of Inspection and Quarantine Technology Research，Fujian Enry-Exit Inspection & Quarantine Bureau of P.R.C, Fuzhou 350001, China
Abstract：Chrysoidin is a kind of banned food dye, and it has been illegally used for coloring food. A rapid detection and quantification method is developed and applied in analysis chrysoidin in yuba. Gold nanoparticles are synthesized by using hexadecyl trimethyl ammonium bromide (CTAB) as the bifunctional ligand to link the solid substrate and the AuNPs. The laser wavelength used for quantitative is 1 594 cm-1. Significant differences between different concentrations of chrysoidin are verified by multiple variable analysis. A relationship between the logarithm of the concentrations and the intensity of laser is proved using univariate analysis method. The calibration curves showed good linearity in the range of 0.001～0.5 mmol·L-1 with correlation coefficients r=0.995. The method is successfully applied to the determination of chrysoidin in yuba. The average recoveries of the drugs spiked at 50 and 500 μg·g-1 levels are 82.4% and 116.9%, and the relative standard deviations (RSD) are 3.8% and 4.0%. The method is simple, rapid, sensitive and accurate in the determination of chrysoidin.
[1] Yu Q, Golden G. Langmuir, 2007, 23(17): 8659. [2] Alvarez-Puebla R, Cui B, Bravo-Vasquez J P, et al. 2007, 111(18): 6720. [3] Li Z, Tong W M, Stickle W F, et al. Langmuir, 2007, 23(9): 5135. [4] Abdelsalam M E, Mahajan S, Bartlett P N, et al，2007, 129(23): 7399. [5] Hulteen J C, Treichel D A, Smith M T, et al. The Journal of Physical Chemistry B, 1999, 103(19): 3854. [6] Jensen T R, Malinsky M D, Haynes C L, et al. The Journal of Physical Chemistry B, 2000, 104(45): 10549. [7] Duval Malinsky M, Kelly K L, Schatz G C, et al. The Journal of Physical Chemistry B, 2001, 105(12): 2343. [8] Liu G, Cai W, Liang C. Crystal Growth and Design, 2008, 8(8): 2748. [9] Wang H, Levin C S, Halas N J. Journal of the American Chemical Society, 2005, 127(43): 14992. [10] Xu Y, Guo L, Huang L, et al. Journal of Colloid and Interface Science, 2013, 409: 32. [11] YUAN Yu-feng, TAO Zhan-hua, LIU Jun-xian, et al(袁玉峰，陶站华，刘军贤，等). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2011, 31(4): 1001. [12] Cheung W, Shadi I T, Xu Y, et al. The Journal of Physical Chemistry C, 2010, 114(16): 7285. [13] Zhang Y, Lai K, Zhou J, et al. Journal of Raman Spectroscopy, 2012, 43(9): 1208. [14] Xie Y, Li Y, Niu L, et al. Talanta, 2012, 100(15): 32. [15] Enustun B V, Turkevich J. Journal of the American Chemical Society, 1963, 85(21): 3317. [16] Polte J, Ahner T T, Delissen F, et al. Journal of the American Chemical Society, 2010, 132(4): 1296. [17] Georgiou G A. Insight-Non-Destructive Testing and Condition Monitoring, 2007, 49(7): 409.
